ST14 Protein (AA 571-855) (His tag)

Catalog No. ABIN7505189

Product Details

Target: ST14 (Suppression of Tumorigenicity 14 (ST14))

Protein Type: Recombinant

Protein Characteristics: AA 571-855

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This ST14 protein is labelled with His tag.

Sequence: Thr 571-Val 855

Characteristics: A DNA sequence encoding the Human ST14/Matriptase protein (Q9Y5Y6) (Thr 571-Val 855) was expressed with N-His tag.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: ST14 (Suppression of Tumorigenicity 14 (ST14))

Alternative Name: ST14 (ST14 Products)

Background:

Abbreviation: ST14,Matriptase

Target Synonym: Epithin,HAI,Membrane type serine protease 1,MTSP1,Prostamin,PRSS14,Serine protease 14,SNC19,ST14,TADG15,TMPRSS14

Background: Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.Defects in ST14 are a cause of ichthyosis autosomal recessive with hypotrichosis (ARIH). ARIH is a skin disorder characterized by congenital ichthyosis associated with the presence of less than the normal amount of hair.

Molecular Weight:

Calculated MW: 31.24 kDa

Observed MW: 35 kDa

UniProt: Q9Y5Y6