MFN2 Protein (AA 350-600) (His tag)
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- Target See all MFN2 Proteins
- MFN2 (Mitofusin 2 (MFN2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 350-600
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MFN2 protein is labelled with His tag.
- Sequence
- Gln 350-Met 600
- Characteristics
- A DNA sequence encoding the Human Mfn2 protein (O95140) (Gln 350-Met 600) was expressed with a N-His&C-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MFN2 Protein
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!Discover Our Predefined Custom Proteins and Custom Protein Services!ProductExpression SystemConjugateOriginPrice starts atExpression System HEK-293 CellsConjugate His tagOrigin HumanPrice starts at $16,231.82Expression System Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin HumanPrice starts at $20,480.57Your project requires further customization? Contact us and discover our custom protein solutions
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- MFN2 (Mitofusin 2 (MFN2))
- Alternative Name
- Mfn2 (MFN2 Products)
- Background
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Abbreviation: Mfn2
Target Synonym: Mitofusin-2,MFN2,
Background: MFN-2 (Mitofusin 2, also Hypertension-related protein 1, Mitochondrial assembly regulatory factor, HSG protein, and Transmembrane GTPase MFN-2) is an 85?100 kDa mitochondrial member of the dynamin family of molecules. It is ubiquitously expressed, and found in both the ER and outer mitochondrial membrane. Through trans-interactions with MFN-1 and/or MFN-2, MFN-2 apparently mediates the fusion of individual mitochondria with either the ER or with adjacent mitochondria. Pertubations with this process result in both a general failure of mitochondria to fuse, and in cell-specific effects such as a reduction in oxidative phosphorylation, a decrease in the axonal transport of mitochondria, and a deficit in the expression of respiratory chain components. MFN-2 has two key domains.
- Molecular Weight
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Calculated MW: 27.5 kDa
Observed MW: 35 kDa
- UniProt
- O95140
- Pathways
- Skeletal Muscle Fiber Development
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