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MFN2 Protein (AA 350-600) (His tag)

MFN2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505289
  • Target See all MFN2 Proteins
    MFN2 (Mitofusin 2 (MFN2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 350-600
    Origin
    • 8
    • 3
    • 1
    Human
    Source
    • 4
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This MFN2 protein is labelled with His tag.
    Sequence
    Gln 350-Met 600
    Characteristics
    A DNA sequence encoding the Human Mfn2 protein (O95140) (Gln 350-Met 600) was expressed with a N-His&C-His tag.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
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    Product
    Expression System
    Conjugate
    Origin
    Price starts at
    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
    Price starts at $16,231.82
    Expression System Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    Price starts at $20,480.57

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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    MFN2 (Mitofusin 2 (MFN2))
    Alternative Name
    Mfn2 (MFN2 Products)
    Background

    Abbreviation: Mfn2

    Target Synonym: Mitofusin-2,MFN2,

    Background: MFN-2 (Mitofusin 2, also Hypertension-related protein 1, Mitochondrial assembly regulatory factor, HSG protein, and Transmembrane GTPase MFN-2) is an 85?100 kDa mitochondrial member of the dynamin family of molecules. It is ubiquitously expressed, and found in both the ER and outer mitochondrial membrane. Through trans-interactions with MFN-1 and/or MFN-2, MFN-2 apparently mediates the fusion of individual mitochondria with either the ER or with adjacent mitochondria. Pertubations with this process result in both a general failure of mitochondria to fuse, and in cell-specific effects such as a reduction in oxidative phosphorylation, a decrease in the axonal transport of mitochondria, and a deficit in the expression of respiratory chain components. MFN-2 has two key domains.

    Molecular Weight

    Calculated MW: 27.5 kDa

    Observed MW: 35 kDa

    UniProt
    O95140
    Pathways
    Skeletal Muscle Fiber Development
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