Annexin a1 Protein (AA 161-346) (GST-His-Tag)

Catalog No. ABIN7505328

Recombinant Annexin a1 protein expressed in Escherichia coli (E. coli).

Quick Overview for Annexin a1 Protein (AA 161-346) (GST-His-Tag) (ABIN7505328)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 161-346

Purification tag / Conjugate: This Annexin a1 protein is labelled with GST-His-Tag.

Sequence: Lys 161-Asn 346

Characteristics: A DNA sequence encoding the Human Annexin A1/ANXA1 protein (P04083) (Lys 161-Asn 346) was expressed with a N-GST&C-His tag.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Alternative Name: Annexin A1

Background:

Abbreviation: Annexin A1,ANXA1

Target Synonym: Annexin A1,Annexin I,Annexin-1,Calpactin II,Calpactin-2,Chromobindin-9,Lipocortin I,Phospholipase A2 Inhibitory Protein,p35

Background: Annexin A1 is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Annexin A1 has anti-inflammatory properties and inhibits phospholipase A2 activity. Annexin A1 also has roles in many diverse cellular functions, such as membrane aggregation, inflammation, phagocytosis, proliferation, apoptosis, and tumorigenesis and cancer development. ANXA1 is strongly expressed on the cell membrane and occasionally in the cytoplasm of tumor cells in 97 % of samples from patients with hairy cell leukemia.

Molecular Weight:

Calculated MW: 45.35 kDa

Observed MW: 45 kDa

UniProt: P04083

Pathways: Hormone Transport