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SF3B3 Protein (AA 250-399) (GST tag)

SF3B3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505334
  • Target See all SF3B3 Proteins
    SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 250-399
    Origin
    • 5
    • 3
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This SF3B3 protein is labelled with GST tag.
    Sequence
    Glu 250-Phe 399
    Characteristics
    A DNA sequence encoding the Human SF3B3 protein (Q15393-3) (Glu 250-Phe 399) was expressed with a GST tag.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product SF3B3 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
    Alternative Name
    SF3B3 (SF3B3 Products)
    Background

    Abbreviation: SF3B3

    Target Synonym: Splicing factor 3B subunit 3,SF3B3,Spliceosome-associated protein 130

    Background: Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

    Molecular Weight

    Calculated MW: 41.39 kDa

    Observed MW: 42 kDa

    UniProt
    Q15393-3
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