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VWF Protein (AA 1498-1665) (His tag)

This Recombinant VWF protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7505396

Quick Overview for VWF Protein (AA 1498-1665) (His tag) (ABIN7505396)

Target

See all VWF Proteins
VWF (Von Willebrand Factor (VWF))

Protein Type

Recombinant

Origin

  • 10
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Mouse

Source

  • 11
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 1498-1665

    Purification tag / Conjugate

    This VWF protein is labelled with His tag.

    Sequence

    Asp 1498-Val 1665

    Characteristics

    A DNA sequence encoding the Mouse VWF protein (Q8CIZ8) (Asp 1498-Val 1665) was expressed with a N-His tag.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    12 months
  • Target

    VWF (Von Willebrand Factor (VWF))

    Alternative Name

    VWF

    Background

    Abbreviation: VWF

    Target Synonym: F8VWF,Von Willebrand Factor,VWD,VWF,Vwf

    Background: Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thrombocytopenic purpura, Stroke, Heyde's syndrome, possibly hemolytic-uremic syndrome and so on.

    Molecular Weight

    Calculated MW: 18.37 kDa

    Observed MW: 20 kDa

    UniProt

    Q8CIZ8
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