IGF2 Protein (AA 25-126) (His tag)

Catalog No. ABIN7505450

This Recombinant IGF2 protein is expressed in Escherichia coli (E. coli).

Quick Overview for IGF2 Protein (AA 25-126) (His tag) (ABIN7505450)

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Protein Type: Recombinant

Origin: Mouse

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 25-126

Purification tag / Conjugate: This IGF2 protein is labelled with His tag.

Sequence: Ala 25-Leu 126

Characteristics: A DNA sequence encoding the mouse IGF-2/IGF-II protein (P09535) (Ala 25-Leu 126) was expressed with N-His.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Alternative Name: IGF-2

Background:

Abbreviation: IGF-2,IGF-II

Target Synonym: Insulin-like growth factor II,Igf2,IGF-II,Multiplication-stimulating polypeptide

Background: Insulin-like growth factor I (also known as somatomedin C and somatomedin A) and insulin-like growth factor II (multiplication stimulating activity or MSA) belong to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGF-I and IGF-II share approximately 70 % sequence identity. Both IGF-I and IGF-II are expressed in many tissues and cell types and may have autocrine, paracrine and endocrine functions. Mature IGF-I and IGF-II are highly conserved (100 % identity between human, bovine and porcine proteins) and exhibit cross-species activity. IGF-II is a potent mitogenic growth factor. However, unlike IGF-I which has important postnatal roles, the growth-promoting function of IGF-II is limited to embryonic development.

Molecular Weight:

Calculated MW: 11.11 kDa

Observed MW: 14 kDa

UniProt: P09535

Pathways: Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation