VWF Protein (AA 49-230) (His tag)

Catalog No. ABIN7505493

Recombinant VWF protein expressed in Escherichia coli (E. coli).

Quick Overview for VWF Protein (AA 49-230) (His tag) (ABIN7505493)

Target: VWF (Von Willebrand Factor (VWF))

Protein Type: Recombinant

Origin: Rat

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 49-230

Purification tag / Conjugate: This VWF protein is labelled with His tag.

Sequence: Lys 49-Asn 230

Characteristics: A DNA sequence encoding the Rat VWF protein (Q62935) (Lys 49-Asn 230) was expressed with a N-His tag.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: VWF (Von Willebrand Factor (VWF))

Alternative Name: VWF

Background:

Abbreviation: VWF

Target Synonym: F8VWF,Von Willebrand Factor,VWD,vWF,VWF

Background: Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thrombocytopenic purpura, Stroke, Heyde's syndrome, possibly hemolytic-uremic syndrome and so on.

Molecular Weight:

Calculated MW: 19.91 kDa

Observed MW: 25 kDa

UniProt: Q62935