IL29 Protein (AA 1-200)
Quick Overview for IL29 Protein (AA 1-200) (ABIN7505594)
Target
See all IL29 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 1-200
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Sequence
- Met1-Thr200
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Characteristics
- A DNA sequence encoding the Human IL-29 Protein(Q8IU54)(1-200)was expressed with a polyhistidine tag at the N-terminus.
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Endotoxin Level
- <1.0 EU per μg of the protein as determined by the LAL method.
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Interleukin 29 (IL29) (AA 22-200) protein (His tag)
IL29 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 29 (IL29) (AA 20-200) protein (His tag)IL29 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
Interleukin 29 (IL29) (AA 20-200) (Active) protein (His tag)IL29 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE. SDS Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- IL29 (Interleukin 29 (IL29))
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Alternative Name
- IL-29
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Background
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Abbreviation: IL-29
Target Synonym: Interferon lambda-1,IFN-lambda-1,ytokine Zcyto21,Interleukin-29,IL29,IFNL1,ZCYTO21
Background: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
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Molecular Weight
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Calculated MW: 22 kDa
Observed MW: 28-35 kDa
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UniProt
- Q8IU54
Target
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