PLAU Protein (AA 1-431) (His tag)
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- Target See all PLAU Proteins
- PLAU (Plasminogen Activator, Urokinase (PLAU))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-431
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PLAU protein is labelled with His tag.
- Sequence
- Met1-Leu431
- Characteristics
- A DNA sequence encoding the Human PLAU protein (P00749) (Met1-Leu431) was expressed with a C-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PLAU Protein
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Plasminogen Activator, Urokinase (PLAU) (AA 21-431) protein (His tag)
PLAU Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Plasminogen Activator, Urokinase (PLAU) (AA 21-430) protein (His tag)PLAU Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Plasminogen Activator, Urokinase (PLAU) (AA 21-431) protein (His-Avi Tag,Biotin)PLAU Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Plasminogen Activator, Urokinase (PLAU) (AA 179-298) protein (His-IF2DI Tag)PLAU Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Plasminogen Activator, Urokinase (PLAU) (AA 21-431) protein (His tag)PLAU Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE. SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- PLAU (Plasminogen Activator, Urokinase (PLAU))
- Alternative Name
- Urokinase (PLAU Products)
- Background
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Abbreviation: Urokinase,uPA
Target Synonym: Urokinase-Type Plasminogen Activator,U-Plasminogen Activator,uPA,PLAU,ATF,BDPLT5,QPD,u-PA,UPA,URK
Background: Recombinant Human Urokinase-Type Plasminogen Activator is a serine protease, which specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. Urokinase-Type Plasminogen Activator is a potent marker of invasion and metastasis in many human cancers associated with breast, colon, stomach, bladder, brain, ovary and endometrium. Human Urokinase-Type Plasminogen Activator is initially synthesized as 431 amino acid precursor with a N-terminal signal peptide residues. The single chain molecule is processed into a disulfide-linked two-chain molecule. There exists two forms A chain, the long A chain contains an EGF-like domain that is responsible for binding of the uPA receptor. The B chain corresponds to the catalytic domain.
- Molecular Weight
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Calculated MW: 47.3 kDa
Observed MW: 45 kDa
- UniProt
- P00749
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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