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CCL5 Protein (His tag)

Recombinant CCL5 protein expressed in Yeast (Pichia pastoris).
Catalog No. ABIN7519851

Quick Overview for CCL5 Protein (His tag) (ABIN7519851)

Target

See all CCL5 Proteins
CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Protein Type

Recombinant

Origin

  • 20
  • 6
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Source

  • 32
  • 8
  • 2
  • 1
  • 1
  • 1
Yeast (Pichia pastoris)

Purity

> 95 % by SDS-PAGE.
  • Purification tag / Conjugate

    This CCL5 protein is labelled with His tag.

    Purpose

    Recombinant Human CCL5/RANTES Protein

    Sequence

    SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS

    Specificity

    Ser24-Ser91

    Sterility

    0.22 μm filtered

    Endotoxin Level

    <0.1EU/μg
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  • Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Supplied as a 0.22 μm filtered solution in PBS, pH 7.4.

    Storage

    -80 °C

    Storage Comment

    This product is stable at ≤ -70°C for up to 1 year from the date of receipt.|For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature.
  • Target

    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

    Alternative Name

    CCL5/RANTES

    Background

    Description: Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.

    Name: D17S136E, eoCP, RANTES, SCYA5, SIS-delta, SISd, TCP228,CCL5

    Gene ID

    6352

    UniProt

    P13501

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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