CCL5 Protein (His tag)
Quick Overview for CCL5 Protein (His tag) (ABIN7519851)
Target
See all CCL5 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CCL5 protein is labelled with His tag.
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Purpose
- Recombinant Human CCL5/RANTES Protein
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Sequence
- SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
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Specificity
- Ser24-Ser91
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- <0.1EU/μg
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as a 0.22 μm filtered solution in PBS, pH 7.4.
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Storage
- -80 °C
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Storage Comment
- This product is stable at ≤ -70°C for up to 1 year from the date of receipt.|For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature.
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- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
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Alternative Name
- CCL5/RANTES
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Background
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Description: Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.
Name: D17S136E, eoCP, RANTES, SCYA5, SIS-delta, SISd, TCP228,CCL5
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Gene ID
- 6352
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UniProt
- P13501
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
Target
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