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CXCL3 Protein

This Recombinant CXCL3 protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7535397

Quick Overview for CXCL3 Protein (ABIN7535397)

Target

See all CXCL3 Proteins
CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))

Protein Type

Recombinant

Origin

  • 9
  • 5
  • 4
  • 1
Human

Source

  • 18
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 85 % by SDS-PAGE.
  • Purpose

    Recombinant Human CXCL3/GRO-gamma/MIP2-beta Protein

    Sequence

    ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN

    Specificity

    Ala35-Asn107

    Sterility

    0.22 μm filtered

    Endotoxin Level

    <1EU/μg
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

    Buffer

    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • Target

    CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))

    Alternative Name

    CXCL3/GRO-gamma/MIP2-beta

    Background

    Description: CXCL3 is involved in migration, invasion, proliferation and tubule formation of trophoblasts and may play a key role in the pathogenesis of preeclampsia. CXCL3 autocrine/paracrine pathways are involved in the development of prostate cancer by regulating the expression of the target genes that are related to the progression of malignancies. CXCL3 is a novel adipokine that facilitates adipogenesis in an autocrine and/or a paracrine manner through induction of c/ebpb and c/ebpd. CXCL3 and its receptor CXCR2 are overexpressed in prostate cancer cells, prostate epithelial cells and prostate cancer tissues, which may play multiple roles in prostate cancer progression and metastasis.

    Name: CXCL3,CINC-2b,GRO3,GROg,MIP-2b,MIP2B,SCYB3

    Gene ID

    2921

    UniProt

    P19876

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Autophagy
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