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MRGPRE Protein

This Synthetic Nanodisc MRGPRE protein is produced in Mammalian Cells.
Catalog No. ABIN7538372

Quick Overview for MRGPRE Protein (ABIN7538372)

Target

See all MRGPRE Proteins
MRGPRE (MAS-Related GPR, Member E (MRGPRE))

Protein Type

Synthetic Nanodisc

Origin

  • 4
  • 2
Human

Source

  • 4
  • 2
Mammalian Cells
  • Purpose

    Human MRGRE full length protein-synthetic nanodisc

    Characteristics

    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
    Price starts at $13,686.36
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    Conjugate Strep Tag
    Origin Human
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  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Expiry Date

    12 months
  • Target

    MRGPRE (MAS-Related GPR, Member E (MRGPRE))

    Alternative Name

    MRGRE

    Background

    Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain.[UniProtKB/Swiss-Prot Function]

    Molecular Weight

    The human full length MRGRE protein has a MW of 34.3kDa

    UniProt

    Q86SM8
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