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Norovirus GI.3 VP1+VP2 protein-VLP

This VLP protein is produced in HEK-293 Cells.
Catalog No. ABIN7538804

Quick Overview for Norovirus GI.3 VP1+VP2 protein-VLP (ABIN7538804)

Target

Norovirus GI.3 VP1+VP2

Protein Type

VLP

Origin

Norovirus

Source

HEK-293 Cells

Application

ELISA, Lateral Flow (LF), Western Blotting (WB)
  • Purpose

    VLP of Norovirus GI.3 (VP1+VP2)

    Characteristics

    Norovirus-like particles (VLP) were produced in HEK cells by co-expression of the VP1 and VP2 protein. The VLPs do not contain the viral genome, cannot replicate and are not infectious.

    Purification

    Polyethylene glycol precipitation

    Biological Activity Comment

    active
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  • Application Notes

    Applications: Immunogenic antigen, antigen for ELISA and Western blot, reference for rapid antigen tests.
    Western blot: 1-10 μg, ELISA: 1-5 μg/mL

    Comment

    Virus-like Particles are multiprotein complexes that resemble a native virus, but lack the genetic information. Therefore, VLPs are safe to handle in numerous fields of applications. For example, VLPs can be applied as antigen in serological assays (e.g. ELISA), or serve as reference material to standardize the performance of different diagnostic tests (e.g. rapid antigen tests or ELISA). Due to the self-adjuvanting properties of VLPs is the most common application of VLPs the use as antigen for immunizations for vaccine development or antibody discovery campaigns.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS

    Storage

    -80 °C

    Storage Comment

    - 80°C
  • Target

    Norovirus GI.3 VP1+VP2

    Target Type

    Viral Protein

    Background

    Noroviruses (formerly known as Norwalk-like viruses) belong to the Caliciviridae family. Noroviruses are found worldwide and usually cause gastrointestinal illnesses.
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