Tmem266 Protein (AA 1-531) (His tag)
custom-made
Tmem266
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all Tmem266 products
- Tmem266 (Transmembrane Protein 266 (Tmem266))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-531
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Tmem266 protein is labelled with His tag.
- Purpose
- Made-to-order recombinant TMEM266 Protein expressed in mammalian cells.
- Sequence
- MAVAPSFNMT NPQPAIEGGI SEVEIISQQV DEETKSIAPV QLVNFAYRDL PLAAVDLSTA GSQLLSNLDE DYQREGSNWL KPCCGKRAAV WQVFLLSASL NSFLVACVIL VVILLTLELL IDIKLLQFSS AFQFAGVIHW ISLVILSVFF SETVLRIVVL GIWDYIENKI EVFDGAVIIL SLAPMVASTV ANGPRSPWDA ISLIIMLRIW RVKRVIDAYV LPVKLEMEMV IQQYEKAKVI QDEQLERLTQ ICQEQGFEIR QLRAHLAQQD LDLAAEREAA LQAPHVLSQP RSRFKVLEAG TWDEETAAES VVEELQPSQE ATMKDDMNSY ISQYYNGPSS DSGVPEPAVC MVTTAAIDIH QPNISSDLFS LDMPLKLGGN GTSATSESAS RSSVTRAQSD SSQTLGSSMD CSTAREEPSS EPGPSPPPLP SQQQVEEATV QDLLSSLSED PCPSQKALDP APLARPSPAG SAQTSPELEH RVSLFNQKNQ EGFTVFQIRP VIHFQPTVPM LEDKFRSLES KEQKLHRVPE A Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Transmembrane Protein 266 (Tmem266) (AA 1-538) protein (His tag)
custom-made Tmem266 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- Tmem266 (Transmembrane Protein 266 (Tmem266))
- Alternative Name
- TMEM266 (Tmem266 Products)
- Background
- Transmembrane protein 266 (hTMEM266) (HV1-related protein 1) (HsHVRP1),FUNCTION: Voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum (PubMed:25165868, PubMed:30810529). Despite the presence of a voltage-sensor segment, does not form a functional ion channel and its precise role remains unclear (PubMed:25165868, PubMed:30810529). Undergoes both rapid and slow structural rearrangements in response to changes in voltage (PubMed:30810529). Contains a zinc-binding site that can regulate the slow conformational transition (PubMed:30810529). {ECO:0000269|PubMed:25165868, ECO:0000269|PubMed:30810529}.
- Molecular Weight
- 58.4 kDa
- UniProt
- Q2M3C6
- AlphaFold
- Q2M3C6
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