TRIM60 Protein (AA 1-471) (His tag)
custom-made
TRIM60
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all TRIM60 Proteins
- TRIM60 (Tripartite Motif Containing 60 (TRIM60))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-471
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TRIM60 protein is labelled with His tag.
- Purpose
- Made-to-order recombinant TRIM60 Protein expressed in mammalian cells.
- Sequence
- MEFVTALVNL QEESSCPICL EYLKDPVTIN CGHNFCRSCL SVSWKDLDDT FPCPVCRFCF PYKSFRRNPQ LRNLTEIAKQ LQIRRSKRKR QKENAMCEKH NQFLTLFCVK DLEILCTQCS FSTKHQKHYI CPIKKAASYH REILEGSLEP LRNNIERVEK VIILQGSKSV ELKKKVEYKR EEINSEFEQI RLFLQNEQEM ILRQIQDEEM NILAKLNENL VELSDYVSTL KHLLREVEGK SVQSNLELLT QAKSMHHKYQ NLKCPELFSF RLTKYGFSLP PQYSGLDRII KPFQVDVILD LNTAHPQLLV SEDRKAVRYE RKKRNICYDP RRFYVCPAVL GSQRFSSGRH YWEVEVGNKP KWILGVCQDC LLRNWQDQPS VLGGFWAIGR YMKSGYVASG PKTTQLLPVV KPSKIGIFLD YELGDLSFYN MNDRSILYTF NDCFTEAVWP YFYTGTDSEP LKICSVSDSE R Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Tripartite Motif Containing 60 (TRIM60) (AA 1-466) protein (His tag)
custom-made TRIM60 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tripartite Motif Containing 60 (TRIM60) (AA 1-471) protein (GST tag)TRIM60 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- TRIM60 (Tripartite Motif Containing 60 (TRIM60))
- Alternative Name
- TRIM60 (TRIM60 Products)
- Background
- Tripartite motif-containing protein 60 (RING finger protein 129) (RING finger protein 33),FUNCTION: E3 SUMO-protein ligase that mediates SUMOylation of TAB2 leading to inhibition of NF-kappa-B and MAPK pathways by suppressing the TRAF6/TAB2/TAK1 complex. {ECO:0000269|PubMed:33184450}.
- Molecular Weight
- 55.1 kDa
- UniProt
- Q495X7
- AlphaFold
- Q495X7
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