TTC15 Protein (AA 1-735) (His tag)

Catalog No. ABIN7544730

Recombinant TTC15 protein expressed in HEK-293 Cells.

Quick Overview for TTC15 Protein (AA 1-735) (His tag) (ABIN7544730)

Target: TTC15 (Tetratricopeptide Repeat Domain 15 (TTC15))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-735

Purification tag / Conjugate: This TTC15 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant TRAPPC12 Protein expressed in mammalian cells.

Sequence: MEDAGGGEET PAPEAPHPPQ LAPPEEQGLL FQEETIDLGG DEFGSEENET ASEGSSPLAD KLNEHMMESV LISDSPNSEG DAGDLGRVRD EAEPGGEGDP GPEPAGTPSP SGEADGDCAP EDAAPSSGGA PRQDAAREVP GSEAARPEQE PPVAEPVPVC TIFSQRAPPA SGDGFEPQMV KSPSFGGASE ASARTPPQVV QPSPSLSTFF GDTAASHSLA SDFFDSFTTS AFISVSNPGA GSPAPASPPP LAVPGTEGRP EPVAMRGPQA AAPPASPEPF AHIQAVFAGS DDPFATALSM SEMDRRNDAW LPGEATRGVL RAVATQQRGA VFVDKENLTM PGLRFDNIQG DAVKDLMLRF LGEKAAAKRQ VLNADSVEQS FVGLKQLISC RNWRAAVDLC GRLLTAHGQG YGKSGLLTSH TTDSLQLWFV RLALLVKLGL FQNAEMEFEP FGNLDQPDLY YEYYPHVYPG RRGSMVPFSM RILHAELQQY LGNPQESLDR LHKVKTVCSK ILANLEQGLA EDGGMSSVTQ EGRQASIRLW RSRLGRVMYS MANCLLLMKD YVLAVEAYHS VIKYYPEQEP QLLSGIGRIS LQIGDIKTAE KYFQDVEKVT QKLDGLQGKI MVLMNSAFLH LGQNNFAEAH RFFTEILRMD PRNAVANNNA AVCLLYLGKL KDSLRQLEAM VQQDPRHYLH ESVLFNLTTM YELESSRSMQ KKQALLEAVA GKEGDSFNTQ CLKLA Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: TTC15 (Tetratricopeptide Repeat Domain 15 (TTC15))

Alternative Name: TRAPPC12

Background: Trafficking protein particle complex subunit 12 (Tetratricopeptide repeat protein 15) (TPR repeat protein 15) (TTC-15) (Trafficking of membranes and mitosis),FUNCTION: Component of the TRAPP complex, which is involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage (PubMed:21525244, PubMed:28777934). Also plays a role in chromosome congression, kinetochore assembly and stability and controls the recruitment of CENPE to the kinetochores (PubMed:25918224). {ECO:0000269|PubMed:21525244, ECO:0000269|PubMed:25918224, ECO:0000269|PubMed:28777934}.

Molecular Weight: 79.4 kDa

UniProt: Q8WVT3

AlphaFold: Q8WVT3