TSR3 Protein (AA 1-312) (His tag)

Catalog No. ABIN7544813

This Recombinant TSR3 protein is expressed in HEK-293 Cells.

Quick Overview for TSR3 Protein (AA 1-312) (His tag) (ABIN7544813)

Target: TSR3 (TSR3 20S rRNA Accumulation (TSR3))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-312

Purification tag / Conjugate: This TSR3 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant TSR3 Protein expressed in mammalian cells.

Sequence: MGRRRAARGP GAEGGRPRHL PTRSLEAFAE EVGAALQASV EPGAADGEGG PGPAALPCTL AMWELGHCDP RRCTGRKLAR LGLVRCLRLG HRFGGLVLSP VGKQYASPAD RQLVAQSGVA VIDCSWARLD ETPFGKMRGS HLRLLPYLVA ANPVNYGRPY RLSCVEAFAA TFCIVGFPDL AVILLRKFKW GKGFLDLNRQ LLDKYAACGS PEEVLQAEQE FLANAKESPQ EEEIDPFDVD SGREFGNPNR PVASTRLPSD TDDSDASEDP GPGAERGGAS SSCCEEEQTQ GRGAEARAPA EVWKGIKKRQ RD Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: TSR3 (TSR3 20S rRNA Accumulation (TSR3))

Alternative Name: TSR3

Background: 18S rRNA aminocarboxypropyltransferase (EC 2.5.1.-) (20S S rRNA accumulation protein 3 homolog) (HsTsr3),FUNCTION: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA (Probable). It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA (Probable). {ECO:0000305|PubMed:27084949}.

Molecular Weight: 33.6 kDa

UniProt: Q9UJK0

AlphaFold: Q9UJK0