UTP6 Protein (AA 1-597) (His tag)

Catalog No. ABIN7544997

Product Details

Target: UTP6 (UTP6, Small Subunit (SSU) Processome Component, Homolog (UTP6))

Protein Type: Recombinant

Protein Characteristics: AA 1-597

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This UTP6 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant UTP6 Protein expressed in mammalian cells.

Sequence: MAEIIQERIE DRLPELEQLE RIGLFSHAEI KAIIKKASDL EYKIQRRTLF KEDFINYVQY EINLLELIQR RRTRIGYSFK KDEIENSIVH RVQGVFQRAS AKWKDDVQLW LSYVAFCKKW ATKTRLSKVF SAMLAIHSNK PALWIMAAKW EMEDRLSSES ARQLFLRALR FHPECPKLYK EYFRMELMHA EKLRKEKEEF EKASMDVENP DYSEEILKGE LAWIIYKNSV SIIKGAEFHV SLLSIAQLFD FAKDLQKEIY DDLQALHTDD PLTWDYVARR ELEIESQTEE QPTTKQAKAV EVGRKEERCC AVYEEAVKTL PTEAMWKCYI TFCLERFTKK SNSGFLRGKR LERTMTVFRK AHELKLLSEC QYKQLSVSLL CYNFLREALE VAVAGTELFR DSGTMWQLKL QVLIESKSPD IAMLFEEAFV HLKPQVCLPL WISWAEWSEG AKSQEDTEAV FKKALLAVIG ADSVTLKNKY LDWAYRSGGY KKARAVFKSL QESRPFSVDF FRKMIQFEKE QESCNMANIR EYYERALREF GSADSDLWMD YMKEELNHPL GRPENCGQIY WRAMKMLQGE SAEAFVAKHA MHQTGHL Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: UTP6 (UTP6, Small Subunit (SSU) Processome Component, Homolog (UTP6))

Alternative Name: UTP6 (UTP6 Products)

Background: U3 small nucleolar RNA-associated protein 6 homolog (Hepatocellular carcinoma-associated antigen 66) (Multiple hat domains protein),FUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA. {ECO:0000269|PubMed:34516797}.

Molecular Weight: 70.2 kDa

UniProt: Q9NYH9

AlphaFold: Q9NYH9