VKORC1 Protein (AA 1-163) (His tag)
custom-made
VKORC1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all VKORC1 Proteins
- VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-163
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This VKORC1 protein is labelled with His tag.
- Purpose
- Made-to-order recombinant VKORC1 Protein expressed in mammalian cells.
- Sequence
- MGSTWGSPGW VRLALCLTGL VLSLYALHVK AARARDRDYR ALCDVGTAIS CSRVFSSRWG RGFGLVEHVL GQDSILNQSN SIFGCIFYTL QLLLGCLRTR WASVLMLLSS LVSLAGSVYL AWILFFVLYD FCIVCITTYA INVSLMWLSF RKVQEPQGKA KRH Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1) (AA 1-163) protein (GST tag)
VKORC1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)VKORC1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))
- Alternative Name
- VKORC1 (VKORC1 Products)
- Background
- Vitamin K epoxide reductase complex subunit 1 (EC 1.17.4.4) (Vitamin K1 2,3-epoxide reductase subunit 1),FUNCTION: Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development. {ECO:0000269|PubMed:14765194, ECO:0000269|PubMed:14765195, ECO:0000269|PubMed:15879509, ECO:0000269|PubMed:16270630, ECO:0000269|PubMed:20978134, ECO:0000269|PubMed:22923610, ECO:0000269|PubMed:33154105}.
- Molecular Weight
- 18.2 kDa
- UniProt
- Q9BQB6
- AlphaFold
- Q9BQB6
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