SLC25A10 Protein (AA 1-287) (His tag)

Catalog No. ABIN7547115

Recombinant SLC25A10 protein expressed in HEK-293 Cells.

Quick Overview for SLC25A10 Protein (AA 1-287) (His tag) (ABIN7547115)

Target: SLC25A10 (Solute Carrier Family 25 (Mitochondrial Carrier, Dicarboxylate Transporter), Member 10 (SLC25A10))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-287

Purification tag / Conjugate: This SLC25A10 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant SLC25A10 Protein expressed in mammalian cells.

Sequence: MAAEARVSRW YFGGLASCGA ACCTHPLDLL KVHLQTQQEV KLRMTGMALR VVRTDGILAL YSGLSASLCR QMTYSLTRFA IYETVRDRVA KGSQGPLPFH EKVLLGSVSG LAGGFVGTPA DLVNVRMQND VKLPQGQRRN YAHALDGLYR VAREEGLRRL FSGATMASSR GALVTVGQLS CYDQAKQLVL STGYLSDNIF THFVASFIAG GCATFLCQPL DVLKTRLMNS KGEYQGVFHC AVETAKLGPL AFYKGLVPAG IRLIPHTVLT FVFLEQLRKN FGIKVPS Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: SLC25A10 (Solute Carrier Family 25 (Mitochondrial Carrier, Dicarboxylate Transporter), Member 10 (SLC25A10))

Alternative Name: SLC25A10

Background: Mitochondrial dicarboxylate carrier (DIC) (Solute carrier family 25 member 10),FUNCTION: Catalyzes the electroneutral exchange or flux of physiologically important metabolites such as dicarboxylates (malonate, malate, succinate), inorganic sulfur-containing anions, and phosphate, across mitochondrial inner membrane (PubMed:29211846). Plays an important role in gluconeogenesis, fatty acid metabolism, urea synthesis, and sulfur metabolism, particularly in liver, by supplying the substrates for the different metabolic processes. Regulates fatty acid release from adipocytes, and contributes to systemic insulin sensitivity (By similarity). {ECO:0000250|UniProtKB:Q9QZD8, ECO:0000269|PubMed:29211846}.

Molecular Weight: 31.3 kDa

UniProt: Q9UBX3

AlphaFold: Q9UBX3

Pathways: Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport