IQCG Protein (AA 1-443) (His tag)

Catalog No. ABIN7548606

Recombinant IQCG protein expressed in HEK-293 Cells.

Quick Overview for IQCG Protein (AA 1-443) (His tag) (ABIN7548606)

Target: IQCG (IQ Motif Containing G (IQCG))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-443

Purification tag / Conjugate: This IQCG protein is labelled with His tag.

Purpose: Predefined custom protein recombinant IQCG Protein expressed in mammalian cells.

Sequence: MEEDSLEDSN LPPKVWHSEM TVSVTGEPPS TVEEEGIPKE TDIEIIPEIP ETLEPLSLPD VLRISAVLED TTDQLSILNY IMPVQYEGRQ SICVKSREMN LEGTNLDKLP MASTITKIPS PLITEEGPNL PEIRHRGRFA VEFNKMQDLV FKKPTRQTIM TTETLKKIQI DRQFFSDVIA DTIKELQDSA TYNSLLQALS KERENKMHFY DIIAREEKGR KQIISLQKQL INVKKEWQFE VQSQNEYIAN LKDQLQEMKA KSNLENRYMK TNTELQIAQT QKKCNRTEEL LVEEIEKLRM KTEEEARTHT EIEMFLRKEQ QKLEERLEFW MEKYDKDTEM KQNELNALKA TKASDLAHLQ DLAKMIREYE QVIIEDRIEK ERSKKKVKQD LLELKSVIKL QAWWRGTMIR REIGGFKMPK DKVDSKDSKG KGKGKDKRRG KKK Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: IQCG (IQ Motif Containing G (IQCG))

Alternative Name: IQCG

Background: Dynein regulatory complex protein 9 (IQ domain-containing protein G),FUNCTION: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (CAMK4) activity, contributes to the regulation of CAMK4 signaling cascades. Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility. {ECO:0000250|UniProtKB:A3KQH2, ECO:0000250|UniProtKB:A8HQ54, ECO:0000250|UniProtKB:Q80W32}.

Molecular Weight: 51.9 kDa

UniProt: Q9H095

AlphaFold: Q9H095