JDP2 Protein (AA 1-163) (His tag)
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- Target See all JDP2 Proteins
- JDP2 (Jun Dimerization Protein 2 (JDP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-163
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This JDP2 protein is labelled with His tag.
- Purpose
- Made-to-order recombinant JDP2 Protein expressed in mammalian cells.
- Sequence
- MMPGQIPDPS VTTGSLPGLG PLTGLPSSAL TVEELKYADI RNLGAMIAPL HFLEVKLGKR PQPVKSELDE EEERRKRRRE KNKVAAARCR NKKKERTEFL QRESERLELM NAELKTQIEE LKQERQQLIL MLNRHRPTCI VRTDSVKTPE SEGNPLLEQL EKK Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Jun Dimerization Protein 2 (JDP2) (AA 1-163) protein (His tag)
custom-made JDP2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Jun Dimerization Protein 2 (JDP2) (AA 1-163) protein (His tag)JDP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Jun Dimerization Protein 2 (JDP2) (AA 1-163) protein (GST tag)JDP2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- JDP2 (Jun Dimerization Protein 2 (JDP2))
- Alternative Name
- JDP2 (JDP2 Products)
- Background
- Jun dimerization protein 2,FUNCTION: Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin. {ECO:0000269|PubMed:12707301, ECO:0000269|PubMed:12903123, ECO:0000269|PubMed:16026868, ECO:0000269|PubMed:16518400}.
- Molecular Weight
- 18.7 kDa
- UniProt
- Q8WYK2
- AlphaFold
- Q8WYK2
- Pathways
- Chromatin Binding
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