LARP4 Protein (AA 1-724) (His tag)

Catalog No. ABIN7548849

Recombinant LARP4 protein expressed in HEK-293 Cells.

Quick Overview for LARP4 Protein (AA 1-724) (His tag) (ABIN7548849)

Target: LARP4 (La Ribonucleoprotein Domain Family, Member 4 (LARP4))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-724

Purification tag / Conjugate: This LARP4 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant LARP4 Protein expressed in mammalian cells.

Sequence: MLLFVEQVAS KGTGLNPNAK VWQEIAPGNT DATPVTHGTE SSWHEIAATS GAHPEGNAEL SEDICKEYEV MYSSSCETTR NTTGIEESTD GMILGPEDLS YQIYDVSGES NSAVSTEDLK ECLKKQLEFC FSRENLSKDL YLISQMDSDQ FIPIWTVANM EEIKKLTTDP DLILEVLRSS PMVQVDEKGE KVRPSHKRCI VILREIPETT PIEEVKGLFK SENCPKVISC EFAHNSNWYI TFQSDTDAQQ AFKYLREEVK TFQGKPIMAR IKAINTFFAK NGYRLMDSSI YSHPIQTQAQ YASPVFMQPV YNPHQQYSVY SIVPQSWSPN PTPYFETPLA PFPNGSFVNG FNSPGSYKTN AAAMNMGRPF QKNRVKPQFR SSGGSEHSTE GSVSLGDGQL NRYSSRNFPA ERHNPTVTGH QEQTYLQKET STLQVEQNGD YGRGRRTLFR GRRRREDDRI SRPHPSTAES KAPTPKFDLL ASNFPPLPGS SSRMPGELVL ENRMSDVVKG VYKEKDNEEL TISCPVPADE QTECTSAQQL NMSTSSPCAA ELTALSTTQQ EKDLIEDSSV QKDGLNQTTI PVSPPSTTKP SRASTASPCN NNINAATAVA LQEPRKLSYA EVCQKPPKEP SSVLVQPLRE LRSNVVSPTK NEDNGAPENS VEKPHEKPEA RASKDYSGFR GNIIPRGAAG KIREQRRQFS HRAIPQGVTR RNGKEQYVPP RSPK Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: LARP4 (La Ribonucleoprotein Domain Family, Member 4 (LARP4))

Alternative Name: LARP4

Background: La-related protein 4 (La ribonucleoprotein domain family member 4),FUNCTION: RNA binding protein that binds to the poly-A tract of mRNA molecules (PubMed:21098120). Associates with the 40S ribosomal subunit and with polysomes (PubMed:21098120). Plays a role in the regulation of mRNA translation (PubMed:21098120). Plays a role in the regulation of cell morphology and cytoskeletal organization (PubMed:21834987, PubMed:27615744). {ECO:0000269|PubMed:21098120, ECO:0000269|PubMed:21834987, ECO:0000269|PubMed:27615744}.

Molecular Weight: 80.6 kDa

UniProt: Q71RC2

AlphaFold: Q71RC2