MC5 Receptor Protein (AA 1-325) (His tag)

Catalog No. ABIN7549278

Recombinant MC5 Receptor protein expressed in HEK-293 Cells.

Quick Overview for MC5 Receptor Protein (AA 1-325) (His tag) (ABIN7549278)

Target: MC5 Receptor (MC5R) (Melanocortin 5 Receptor (MC5R))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-325

Purification tag / Conjugate: This MC5 Receptor protein is labelled with His tag.

Purpose: Predefined custom protein recombinant MC5R Protein expressed in mammalian cells.

Sequence: MNSSFHLHFL DLNLNATEGN LSGPNVKNKS SPCEDMGIAV EVFLTLGVIS LLENILVIGA IVKNKNLHSP MYFFVCSLAV ADMLVSMSSA WETITIYLLN NKHLVIADAF VRHIDNVFDS MICISVVASM CSLLAIAVDR YVTIFYALRY HHIMTARRSG AIIAGIWAFC TGCGIVFILY SESTYVILCL ISMFFAMLFL LVSLYIHMFL LARTHVKRIA ALPGASSARQ RTSMQGAVTV TMLLGVFTVC WAPFFLHLTL MLSCPQNLYC SRFMSHFNMY LILIMCNSVM DPLIYAFRSQ EMRKTFKEII CCRGFRIACS FPRRD Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: MC5 Receptor (MC5R) (Melanocortin 5 Receptor (MC5R))

Alternative Name: MC5R

Background: Melanocortin receptor 5 (MC5-R) (MC-2),FUNCTION: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

Molecular Weight: 36.6 kDa

UniProt: P33032

AlphaFold: P33032

Pathways: cAMP Metabolic Process