PRR7 Protein (AA 1-274) (His tag)
custom-made
PRR7
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all PRR7 Proteins
- PRR7 (Proline Rich 7 (Synaptic) (PRR7))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-274
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PRR7 protein is labelled with His tag.
- Purpose
- Made-to-order recombinant PRR7 Protein expressed in mammalian cells.
- Sequence
- MVMSQGTYTF LTCFAGFWLI WGLIVLLCCF CSFLRRRLKR RQEERLREQN LRALELEPLE LEGSLAGSPP GLAPPQPPPH RSRLEAPAHA HSHPHVHVHP LLHHGPAQPH AHAHPHPHHH ALPHPPPTHL SVPPRPWSYP RQAESDMSKP PCYEEAVLMA EPPPPYSEVL TDTRGLYRKI VTPFLSRRDS AEKQEQPPPS YKPLFLDRGY TSALHLPSAP RPAPPCPALC LQADRGRRVF PSWTDSELSS REPLEHGAWR LPVSIPLFGR TTAV Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Proline Rich 7 (Synaptic) (PRR7) (AA 1-269) protein (His tag)
custom-made PRR7 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Proline Rich 7 (Synaptic) (PRR7) (AA 1-274) protein (GST tag)PRR7 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- PRR7 (Proline Rich 7 (Synaptic) (PRR7))
- Alternative Name
- PRR7 (PRR7 Products)
- Background
- Proline-rich protein 7 (Synaptic proline-rich membrane protein),FUNCTION: Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (By similarity). Inhibits ubiquitination-mediated degradation and promotes phosphorylation and transcriptional activity of transcription factor JUN (PubMed:27458189). Might play a redundant role in the regulation of T cell receptor signaling (PubMed:21460222). Might promote apoptosis in T cells (PubMed:21460222). {ECO:0000250|UniProtKB:P0C6T3, ECO:0000250|UniProtKB:Q3V0I2, ECO:0000269|PubMed:21460222, ECO:0000269|PubMed:27458189}.
- Molecular Weight
- 30.9 kDa
- UniProt
- Q8TB68
- AlphaFold
- Q8TB68
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