CADPS2 Protein (AA 1-1296) (His tag)

Catalog No. ABIN7552964

This Recombinant CADPS2 protein is expressed in HEK-293 Cells.

Quick Overview for CADPS2 Protein (AA 1-1296) (His tag) (ABIN7552964)

Target: CADPS2 (Ca++-Dependent Secretion Activator 2 (CADPS2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-1296

Purification tag / Conjugate: This CADPS2 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant CADPS2 Protein expressed in mammalian cells.

Sequence: MLDPSSSEEE SDEGLEEESR DVLVAAGSSQ RAPPAPTREG RRDAPGRAGG GGAARSVSPS PSVLSEGRDE PQRQLDDEQE RRIRLQLYVF VVRCIAYPFN AKQPTDMARR QQKLNKQQLQ LLKERFQAFL NGETQIVADE AFCNAVRSYY EVFLKSDRVA RMVQSGGCSA NDFREVFKKN IEKRVRSLPE IDGLSKETVL SSWIAKYDAI YRGEEDLCKQ PNRMALSAVS ELILSKEQLY EMFQQILGIK KLEHQLLYNA CQLDNADEQA AQIRRELDGR LQLADKMAKE RKFPKFIAKD MENMYIEELR SSVNLLMANL ESLPVSKGGP EFKLQKLKRS QNSAFLDIGD ENEIQLSKSD VVLSFTLEIV IMEVQGLKSV APNRIVYCTM EVEGEKLQTD QAEASRPQWG TQGDFTTTHP RPVVKVKLFT ESTGVLALED KELGRVILYP TSNSSKSAEL HRMVVPKNSQ DSDLKIKLAV RMDKPAHMKH SGYLYALGQK VWKRWKKRYF VLVQVSQYTF AMCSYREKKS EPQELMQLEG YTVDYTDPHP GLQGGCMFFN AVKEGDTVIF ASDDEQDRIL WVQAMYRATG QSYKPVPAIQ TQKLNPKGGT LHADAQLSGK DADRFQKHGM DEFISANPCK LDHAFLFRIL QRQTLDHRLN DSYSCLGWFS PGQVFVLDEY CARYGVRGCH RHLCYLAELM EHSENGAVID PTLLHYSFAF CASHVHGNRP DGIGTVSVEE KERFEEIKER LSSLLENQIS HFRYCFPFGR PEGALKATLS LLERVLMKDI ATPIPAEEVK KVVRKCLEKA ALINYTRLTE YAKIEETMNQ ASPARKLEEI LHLAELCIEV LQQNEEHHAE GREAFAWWPD LLAEHAEKFW ALFTVDMDTA LEAQPQDSWD SFPLFQLLNN FLRNDTLLCN GKFHKHLQEI FVPLVVRYVD LMESSIAQSI HRGFEQETWQ PVKNIANSLP NVALPKVPSL PLNLPQIPNI STASWMPSLY ESTNGSATSE DLFWKLDALQ MFVFDLHWPE QEFAHHLEQR LKLMASDMLE ACVKRTRTAF ELKLQKASKT TDLRIPASVC TMFNVLVDAK KQSTKLCALD GGQEQQYHSK IDDLIDNSVK EIISLLVSKF VSVLEGVLSK LSRYDEGTFF SSILSFTVKA AAKYVDVPKP GMDLADTYIM FVRQNQDILR EKVNEEMYIE KLFDQWYSSS MKVICVWLTD RLDLQLHIYQ LKTLIKIVKK TYRDFRLQGV LEGTLNSKTY DTVHRRLTVE EATASVSEGG GLQGITMKDS DEEEEG Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: CADPS2 (Ca++-Dependent Secretion Activator 2 (CADPS2))

Alternative Name: CADPS2

Background: Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2),FUNCTION: Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles (By similarity). {ECO:0000250}.

Molecular Weight: 147.7 kDa

UniProt: Q86UW7

AlphaFold: Q86UW7

Pathways: Synaptic Vesicle Exocytosis