DDX31 Protein (AA 1-851) (His tag)

Catalog No. ABIN7553641

Product Details

Target: DDX31 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 31 (DDX31))

Protein Type: Recombinant

Protein Characteristics: AA 1-851

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This DDX31 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant DDX31 Protein expressed in mammalian cells.

Sequence: MAPDLASQRH SESFPSVNSR PNVILPGREG RREGLPPGGG TRGSLVPTRP VPPSPAPLGT SPYSWSRSGP GRGGGAGSSR VPRGVPGPAV CAPGSLLHHA SPTQTMAAAD GSLFDNPRTF SRRPPAQASR QAKATKRKYQ ASSEAPPAKR RNETSFLPAK KTSVKETQRT FKGNAQKMFS PKKHSVSTSD RNQEERQCIK TSSLFKNNPD IPELHRPVVK QVQEKVFTSA AFHELGLHPH LISTINTVLK MSSMTSVQKQ SIPVLLEGRD ALVRSQTGSG KTLAYCIPVV QSLQAMESKI QRSDGPYALV LVPTRELALQ SFDTVQKLLK PFTWIVPGVL MGGEKRKSEK ARLRKGINIL ISTPGRLVDH IKSTKNIHFS RLRWLVFDEA DRILDLGFEK DITVILNAVN AECQKRQNVL LSATLTEGVT RLADISLHDP VSISVLDKSH DQLNPKDKAV QEVCPPPAGD KLDSFAIPES LKQHVTVVPS KLRLVCLAAF ILQKCKFEED QKMVVFFSSC ELVEFHYSLF LQTLLSSSGA PASGQLPSAS MRLKFLRLHG GMEQEERTAV FQEFSHSRRG VLLCTDVAAR GLDLPQVTWI VQYNAPSSPA EYIHRIGRTA RIGCHGSSLL ILAPSEAEYV NSLASHKINV SEIKMEDILC VLTRDDCFKG KRWGAQKSHA VGPQEIRERA TVLQTVFEDY VHSSERRVSW AKKALQSFIQ AYATYPRELK HIFHVRSLHL GHVAKSFGLR DAPRNLSALT RKKRKAHVKR PDLHKKTQSK HSLAEILRSE YSSGMEADIA KVKKQNAPGE PGGRPLQHSL QPTPCFGRGK TLKWRKTQKG VQRDSKTSQK V Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: DDX31 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 31 (DDX31))

Alternative Name: DDX31 (DDX31 Products)

Background: Probable ATP-dependent RNA helicase DDX31 (EC 3.6.4.13) (DEAD box protein 31) (Helicain),FUNCTION: Probable ATP-dependent RNA helicase (By similarity). Plays a role in ribosome biogenesis and TP53/p53 regulation through its interaction with NPM1 (PubMed:23019224). {ECO:0000250, ECO:0000269|PubMed:23019224}.

Molecular Weight: 94.1 kDa

UniProt: Q9H8H2

AlphaFold: Q9H8H2