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EWSR1 Protein (AA 1-656) (His tag)

This Recombinant EWSR1 protein is expressed in HEK-293 Cells.
Catalog No. ABIN7553876

Quick Overview for EWSR1 Protein (AA 1-656) (His tag) (ABIN7553876)

Target

See all EWSR1 Proteins
EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

Protein Type

Recombinant

Origin

  • 3
  • 1
Human

Source

  • 2
  • 1
  • 1
HEK-293 Cells

Purity

> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade

custom-made
  • Protein Characteristics

    AA 1-656

    Purification tag / Conjugate

    This EWSR1 protein is labelled with His tag.

    Purpose

    Predefined custom protein recombinant EWSR1 Protein expressed in mammalian cells.

    Sequence

    MASTDYSTYS QAAAQQGYSA YTAQPTQGYA QTTQAYGQQS YGTYGQPTDV SYTQAQTTAT YGQTAYATSY GQPPTGYTTP TAPQAYSQPV QGYGTGAYDT TTATVTTTQA SYAAQSAYGT QPAYPAYGQQ PAATAPTRPQ DGNKPTETSQ PQSSTGGYNQ PSLGYGQSNY SYPQVPGSYP MQPVTAPPSY PPTSYSSTQP TSYDQSSYSQ QNTYGQPSSY GQQSSYGQQS SYGQQPPTSY PPQTGSYSQA PSQYSQQSSS YGQQSSFRQD HPSSMGVYGQ ESGGFSGPGE NRSMSGPDNR GRGRGGFDRG GMSRGGRGGG RGGMGSAGER GGFNKPGGPM DEGPDLDLGP PVDPDEDSDN SAIYVQGLND SVTLDDLADF FKQCGVVKMN KRTGQPMIHI YLDKETGKPK GDATVSYEDP PTAKAAVEWF DGKDFQGSKL KVSLARKKPP MNSMRGGLPP REGRGMPPPL RGGPGGPGGP GGPMGRMGGR GGDRGGFPPR GPRGSRGNPS GGGNVQHRAG DWQCPNPGCG NQNFAWRTEC NQCKAPKPEG FLPPPFPPPG GDRGRGGPGG MRGGRGGLMD RGGPGGMFRG GRGGDRGGFR GGRGMDRGGF GGGRRGGPGG PPGPLMEQMG GRRGGRGGPG KMDKGEHRQE RRDRPY Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

    Specificity

    If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

    Characteristics

    Key Benefits:
    • Predefined custom protein - from design to production - by highly experienced protein experts.
    • Protein expressed in mammalian cells and purified in one-step affinity chromatography
    • The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
    • State-of-the-art algorithm used for plasmid design (Gene synthesis).
    This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

    If you are not interested in a full length protein, please contact us for individual protein fragments.

    The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
  • Want other Options for this Protein ?

    !
    Discover Our Catalog and Custom Protein Service Options!
    Product
    Expression System
    Conjugate
    Origin
    Price
    Expression System Wheat germ
    Conjugate GST tag
    Origin Human
    Price $605.74
    Expression System HEK-293 Cells
    Conjugate Myc-DYKDDDDK Tag
    Origin Human
    Price $956.40
    Expression System Escherichia coli (E. coli)
    Conjugate His-SUMO Tag
    Origin Human
    Price $663.94

    Your project requires further customization? Contact us and discover our custom protein solutions

  • Application Notes

    We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    The buffer composition is at the discretion of the manufacturer.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C.

    Expiry Date

    12 months
  • Target

    EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

    Alternative Name

    EWSR1

    Background

    RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein),FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

    Molecular Weight

    68.5 kDa

    UniProt

    Q01844

    AlphaFold

    Q01844
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