HERC6 Protein (AA 1-1022) (His tag)

Catalog No. ABIN7554087

Recombinant HERC6 protein expressed in HEK-293 Cells.

Quick Overview for HERC6 Protein (AA 1-1022) (His tag) (ABIN7554087)

Target: HERC6 (HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 6 (HERC6))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-1022

Purification tag / Conjugate: This HERC6 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant HERC6 Protein expressed in mammalian cells.

Sequence: MYFCWGADSR ELQRRRTAGS PGAELLQAAS GERHSLLLLT NHRVLSCGDN SRGQLGRRGA QRGELPEPIQ ALETLIVDLV SCGKEHSLAV CHKGRVFAWG AGSEGQLGIG EFKEISFTPK KIMTLNDIKI IQVSCGHYHS LALSKDSQVF SWGKNSHGQL GLGKEFPSQA SPQRVRSLEG IPLAQVAAGG AHSFALSLCG TSFGWGSNSA GQLALSGRNV PVQSNKPLSV GALKNLGVVY ISCGDAHTAV LTQDGKVFTF GDNRSGQLGY SPTPEKRGPQ LVERIDGLVS QIDCGSYHTL AYVHTTGQVV SFGHGPSDTS KPTHPEALTE NFDISCLISA EDFVDVQVKH IFAGTYANFV TTHQDTSSTR APGKTLPEIS RISQSMAEKW IAVKRRSTEH EMAKSEIRMI FSSPACLTAS FLKKRGTGET TSIDVDLEMA RDTFKKLTKK EWISSMITTC LEDDLLRALP CHSPHQEALS VFLLLPECPV MHDSKNWKNL VVPFAKAVCE MSKQSLQVLK KCWAFLQESS LNPLIQMLKA AIISQLLHQT KTEQDHCNVK ALLGMMKELH KVNKANCRLP ENTFNINELS NLLNFYIDRG RQLFRDNHLI PAETPSPVIF SDFPFIFNSL SKIKLLQADS HIKMQMSEKK AYMLMHETIL QKKDEFPPSP RFILRVRRSR LVKDALRQLS QAEATDFCKV LVVEFINEIC PESGGVSSEF FHCMFEEMTK PEYGMFMYPE MGSCMWFPAK PKPEKKRYFL FGMLCGLSLF NLNVANLPFP LALYKKLLDQ KPSLEDLKEL SPRLGKSLQE VLDDAADDIG DALCIRFSIH WDQNDVDLIP NGISIPVDQT NKRDYVSKYI DYIFNVSVKA VYEEFQRGFY RVCEKEILRH FYPEELMTAI IGNTDYDWKQ FEQNSKYEQG YQKSHPTIQL FWKAFHKLTL DEKKKFLFFL TGRDRLHARG IQKMEIVFRC PETFSERDHP TSITCHNILS LPKYSTMERM EEALQVAINN NRGFVSPMLT QS Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: HERC6 (HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 6 (HERC6))

Alternative Name: HERC6

Background: Probable E3 ubiquitin-protein ligase HERC6 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 6) (HECT-type E3 ubiquitin transferase HERC6),FUNCTION: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. {ECO:0000250}.

Molecular Weight: 115.1 kDa

UniProt: Q8IVU3

AlphaFold: Q8IVU3