MICAL-Like 1 Protein (MICALL1) (AA 1-863) (His tag)

Catalog No. ABIN7554560

This Recombinant MICAL-Like 1 protein is expressed in HEK-293 Cells.

Quick Overview for MICAL-Like 1 Protein (MICALL1) (AA 1-863) (His tag) (ABIN7554560)

Target: MICAL-Like 1 (MICALL1)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-863

Purification tag / Conjugate: This MICAL-Like 1 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant MICALL1 Protein expressed in mammalian cells.

Sequence: MAGPRGALLA WCRRQCEGYR GVEIRDLSSS FRDGLAFCAI LHRHRPDLLD FDSLSKDNVF ENNRLAFEVA EKELGIPALL DPNDMVSMSV PDCLSIMTYV SQYYNHFCSP GQAGVSPPRK GLAPCSPPSV APTPVEPEDV AQGEELSSGS LSEQGTGQTP SSTCAACQQH VHLVQRYLAD GRLYHRHCFR CRRCSSTLLP GAYENGPEEG TFVCAEHCAR LGPGTRSGTR PGPFSQPKQQ HQQQLAEDAK DVPGGGPSSS APAGAEADGP KASPEARPQI PTKPRVPGKL QELASPPAGR PTPAPRKASE STTPAPPTPR PRSSLQQENL VEQAGSSSLV NGRLHELPVP KPRGTPKPSE GTPAPRKDPP WITLVQAEPK KKPAPLPPSS SPGPPSQDSR QVENGGTEEV AQPSPTASLE SKPYNPFEEE EEDKEEEAPA APSLATSPAL GHPESTPKSL HPWYGITPTS SPKTKKRPAP RAPSASPLAL HASRLSHSEP PSATPSPALS VESLSSESAS QTAGAELLEP PAVPKSSSEP AVHAPGTPGN PVSLSTNSSL ASSGELVEPR VEQMPQASPG LAPRTRGSSG PQPAKPCSGA TPTPLLLVGD RSPVPSPGSS SPQLQVKSSC KENPFNRKPS PAASPATKKA TKGSKPVRPP APGHGFPLIK RKVQADQYIP EEDIHGEMDT IERRLDALEH RGVLLEEKLR GGLNEGREDD MLVDWFKLIH EKHLLVRRES ELIYVFKQQN LEQRQADVEY ELRCLLNKPE KDWTEEDRAR EKVLMQELVT LIEQRNAIIN CLDEDRQREE EEDKMLEAMI KKKEFQREAE PEGKKKGKFK TMKMLKLLGN KRDAKSKSPR DKS Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: MICAL-Like 1 (MICALL1)

Alternative Name: MICALL1

Background: MICAL-like protein 1 (Molecule interacting with Rab13) (MIRab13),FUNCTION: Probable lipid-binding protein with higher affinity for phosphatidic acid, a lipid enriched in recycling endosome membranes. On endosome membranes, may act as a downstream effector of Rab proteins recruiting cytosolic proteins to regulate membrane tubulation. May be involved in a late step of receptor-mediated endocytosis regulating for instance endocytosed-EGF receptor trafficking. Alternatively, may regulate slow endocytic recycling of endocytosed proteins back to the plasma membrane. May indirectly play a role in neurite outgrowth. {ECO:0000269|PubMed:19864458, ECO:0000269|PubMed:20801876, ECO:0000269|PubMed:21795389, ECO:0000269|PubMed:23596323}.

Molecular Weight: 93.4 kDa

UniProt: Q8N3F8

AlphaFold: Q8N3F8