REXO1 Protein (AA 1-1221) (His tag)

Catalog No. ABIN7555200

Product Details

Target: REXO1 (REX1, RNA Exonuclease 1 Homolog (REXO1))

Protein Type: Recombinant

Protein Characteristics: AA 1-1221

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This REXO1 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant REXO1 Protein expressed in mammalian cells.

Sequence: MLRSTGFFRA IDCPYWSGAP GGPCRRPYCH FRHRGARGSG APGDGGEAPP AAGLGYDPYN PELPKPPAQR ENGTLGLGEE PRPDVLELEL VNQAIEAVRS EVELEQRRYR ELLETTREHR SAEAPALAPR GPNASPTVGP DEDAFPLAFD YSPGSHGLLS PDAGYQPTPL AAPAEPGSKY SLASLDRGQG RGGGGGGALE YVPKAVSQPR RHSRPVPSGK YVVDNSRPPT DLEYDPLSNY SARHLSRASS RDERAAKRPR GSRGSEPYTP APKKLCDPFG SCDARFSDSE DEAATVPGNE PTTASTPKAR ADPEIKATGQ PPSKEGLEAE GGGLRETKET AVQCDVGDLQ PPPAKPASPA QVQSSQDGGC PKEGKPKKKK TGAPPAPSCK DGAQGKDKTK DKGRGRPVEK PRADKKGPQA SSPRRKAERP EGTKKKPSSA TPVATSGKGR PDRPARRPSP TSGDSRPAAG RGPPRPLQLP DRKSTKAPSG KLVERKARSL DEGASQDAPK LKKRALSHAD LFGDESEDEA AGPGVPSVWP SALPSLSSDS DSDSDSSLGF PEAQGPPKRL KASPPPSPAP SSSSSSSSST SSAGADVDYS ALEKEVDFDS DPMEECLRIF NESTSVKTED RGRLARQPPK EEKSEEKGLS GLTTLFPGQK RRISHLSKQG QEVEPPRRGP AVPPARPPTA QEVCYLRAQQ AQRASASLLQ APARLAEKSP SVHISAPGEK RRIAHIPNPR LAAAPTGAKR TLAASGSQSS NGPEPGGQQL KTRTLSGMAS KTTTTIIPKR IAHSPSLQSL KKPIIPKEFG GKVPTVIRQR YLNLFIEECL KFCTSNQEAI EKALNEEKVA YDRSPSKNIY LNVAVNTLKK LRGLAPSAVP GLSKTSGRRV VSHEVVLGGR LAAKTSFSLS RPSSPRVEDL KGAALYSRLR EYLLTQDQLK ENGYPFPHPE RPGGAIIFTA EEKRPKDSSC RTCCRCGTEY LVSSSGRCIR DEECYYHWGR LRRNRVAGGW ETQYMCCSAA AGSVGCQVAK QHVQDGRKER LEGFVKTFEK ELSGDTHPGI YALDCEMSYT TYGLELTRVT VVDTDVHVVY DTFVKPDNEI VDYNTRFSGV TEADLADTSV TLRDVQAVLL SMFSADTILI GHSLESDLLA LKVIHSTVVD TSVLFPHRLG LPYKRSLRNL MADYLRQIIQ DNVDGHSSSE DAGACMHLVI WKVREDAKTK R Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: REXO1 (REX1, RNA Exonuclease 1 Homolog (REXO1))

Alternative Name: REXO1 (REXO1 Products)

Background: RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin-A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1),FUNCTION: Seems to have no detectable effect on transcription elongation in vitro. {ECO:0000269|PubMed:12943681}.

Molecular Weight: 131.5 kDa

UniProt: Q8N1G1

AlphaFold: Q8N1G1