ZNF827 Protein (AA 1-1081) (His tag)

Catalog No. ABIN7556136

Recombinant ZNF827 protein expressed in HEK-293 Cells.

Quick Overview for ZNF827 Protein (AA 1-1081) (His tag) (ABIN7556136)

Target: ZNF827 (Zinc Finger Protein 827 (ZNF827))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-1081

Purification tag / Conjugate: This ZNF827 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant ZNF827 Protein expressed in mammalian cells.

Sequence: MPRRKQEQPK RLPSHVSRQE EAEGELSEGE HWYGNSSETP SEASYGEVQE NYKLSLEDRI QEQSTSPDTS LGSTTPSSHT LELVALDSEV LRDSLQCQDH LSPGVSSLCD DDPGSNKPLS SNLRRLLEAG SLKLDAAATA NGRVESPVNV GSNLSFSPPS HHAQQLSVLA RKLAEKQEQN DQYTPSNRFI WNQGKWLPNS TTTCSLSPDS AILKLKAAAN AVLQDKSLTR TEETMRFESF SSPFSSQSAS STLAALSKKV SERSLTPGQE HPPPASSFLS LASMTSSAAL LKEVAARAAG SLLAEKSSLL PEDPLPPPPS EKKPEKVTPP PPPPPPPPPP PPPQSLELLL LPVPKGRVSK PSNSASEEES GKPFQCPICG LVIKRKSYWK RHMVIHTGLK SHQCPLCPFR CARKDNLKSH MKVHQHQDRG ETFQCQLCPF TSSRHFSLKL HMRCHQHFLR TEAKVKEEIP DPDVKGSPHL SDSACLGQQR EGGGTELVGT MMTSNTPERT SQGGAGVSPL LVKEEPKEDN GLPTSFTLNA ADRPANHTKL KDPSEYVANS ASALFSQDIS VKMASDFLMK LSAANQKEPM NLNFKVKEEP KEGESLSTTL PRSSYVFSPE SEVSAPGVSE DALKPQEGKG SVLRRDVSVK AASELLMKLS AESYKETQMV KIKEEPMEVD IQDSHVSISP SRNVGYSTLI GREKTEPLQK MPEGRVPPER NLFSQDISVK MASELLFQLS EKVSKEHNHT KENTIRTTTS PFFSEDTFRQ SPFTSNSKEL LPSDSVLHGR ISAPETEKIV LEAGNGLPSW KFNDQLFPCD VCGKVFGRQQ TLSRHLSLHT EERKYKCHLC PYAAKCRANL NQHLTVHSVK LVSTDTEDIV SAVTSEGSDG KKHPYYYSCH VCGFETELNV QFVSHMSLHV DKEQWMFSIC CTACDFVTME EAEIKTHIGT KHTGEDRKTP SESNSPSSSS LSALSDSANS KDDSDGSQKN KGGNNLLVIS VMPGSQPSLN SEEKPEKGFE CVFCNFVCKT KNMFERHLQI HLITRMFECD VCHKFMKTPE QLLEHKKCHT VPTGGLNSGQ W Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: ZNF827 (Zinc Finger Protein 827 (ZNF827))

Alternative Name: ZNF827

Background: Zinc finger protein 827,FUNCTION: As part of a ribonucleoprotein complex composed at least of HNRNPK, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation (PubMed:33174841). Could also recruit the nucleosome remodeling and histone deacetylase/NuRD complex to telomeric regions of chromosomes to regulate chromatin remodeling as part of telomere maintenance (PubMed:25150861). {ECO:0000269|PubMed:25150861, ECO:0000269|PubMed:33174841}.

Molecular Weight: 119.2 kDa

UniProt: Q17R98

AlphaFold: Q17R98