ARRDC4 Protein (AA 1-415) (His tag)
custom-made
ARRDC4
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all ARRDC4 products
- ARRDC4 (Arrestin Domain Containing 4 (ARRDC4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-415
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ARRDC4 protein is labelled with His tag.
- Purpose
- Made-to-order recombinant Arrdc4 Protein expressed in mammalian cells.
- Sequence
- MGGEAGADGP RGRVKSLGLV FEDESKGCYS SGETVAGHVL LEAAEPVALR GLRLEAQGRA TSAWGPSAGA RVCIGGGSPA ASSEVEYLNL RLSLLEAPAG EGVTLLQPGK HEFPFRFQLP SEPLATSFTG KYGSIQYCVR AVLERPQVPD QSVRRELQVV SHVDVNTPPL LTPMLKTQEK MVGCWLFTSG PVSLSVKIER KGYCNGEAIP IYAEIENCSS RLVVPKAAIF QTQTYLASGK TKTVRHMVAN VRGNHIGSGS TDTWNGKMLK IPPVTPSILD CCIIRVDYSL AVYIHIPGAK RLMLELPLVI GTIPYSGFGR RNSSVASQFS MDMCWLALAL PEQPEAPPNY ADVVSEEEFS RHVPPYPQPS DCDGEACYSM FACIQEFRFQ PPPLYSEVDP HPGDAQETQP VSFIL Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Arrestin Domain Containing 4 (ARRDC4) (AA 1-418) protein (His tag)
custom-made ARRDC4 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Arrestin Domain Containing 4 (ARRDC4) (AA 1-418) protein (GST tag)ARRDC4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- ARRDC4 (Arrestin Domain Containing 4 (ARRDC4))
- Alternative Name
- Arrdc4 (ARRDC4 Products)
- Background
- Arrestin domain-containing protein 4,FUNCTION: Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:27462458). Plays a role in endocytosis of activated G protein-coupled receptors (GPCRs) (By similarity). Through an ubiquitination-dependent mechanism also plays a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458). May play a role in glucose uptake (By similarity). Participates in innate immune response by promoting IFIH1/MDA5 activation through interaction with TRIM65 (By similarity). {ECO:0000250|UniProtKB:Q8NCT1, ECO:0000269|PubMed:27462458}.
- Molecular Weight
- 45.0 kDa
- UniProt
- A0A0B4J1F4
- AlphaFold
- A0A0B4J1F4
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