SOX4 Protein (AA 1-440) (His tag)

Catalog No. ABIN7556907

Recombinant SOX4 protein expressed in HEK-293 Cells.

Quick Overview for SOX4 Protein (AA 1-440) (His tag) (ABIN7556907)

Target: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-440

Purification tag / Conjugate: This SOX4 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Sox4 Protein expressed in mammalian cells.

Sequence: MVQQTNNAEN TEALLAGESS DSGAGLELGI ASSPTPGSTA STGGKADDPS WCKTPSGHIK RPMNAFMVWS QIERRKIMEQ SPDMHNAEIS KRLGKRWKLL KDSDKIPFIQ EAERLRLKHM ADYPDYKYRP RKKVKSGNAG AGSAATAKPG EKGDKVAGSS GHAGSSHAGG GAGGSSKPAP KKSCGPKVAG SSVGKPHAKL VPAGGSKAAA SFSPEQAALL PLGEPTAVYK VRTPSAATPA ASSSPSSALA TPAKHPADKK VKRVYLFGSL GASASPVGGL GASADPSDPL GLYEDGGPGC SPDGRSLSGR SSAASSPAAS RSPADHRGYA SLRAASPAPS SAPSHASSSL SSSSSSSSGS SSSDDEFEDD LLDLNPSSNF ESMSLGSFSS SSALDRDLDF NFEPGSGSHF EFPDYCTPEV SEMISGDWLE SSISNLVFTY Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Alternative Name: Sox4

Background: Transcription factor SOX-4,FUNCTION: Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif (PubMed:8404853). Required for IL17A-producing Vgamma2-positive gamma-delta T-cell maturation and development, via binding to regulator loci of RORC to modulate expression (PubMed:23562159). Involved in skeletal myoblast differentiation by promoting gene expression of CALD1 (PubMed:26291311). {ECO:0000269|PubMed:23562159, ECO:0000269|PubMed:26291311, ECO:0000269|PubMed:8404853}.

Molecular Weight: 45.0 kDa

UniProt: Q06831

AlphaFold: Q06831