Fascin 2 Protein (FSCN2) (AA 1-492) (His tag)

Catalog No. ABIN7557021

Recombinant Fascin 2 protein expressed in HEK-293 Cells.

Quick Overview for Fascin 2 Protein (FSCN2) (AA 1-492) (His tag) (ABIN7557021)

Target: Fascin 2 (FSCN2)

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-492

Purification tag / Conjugate: This Fascin 2 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Fscn2 Protein expressed in mammalian cells.

Sequence: MPTNGLHQVL KIQFGLVNDA DRYLTAESFG FKVNASAASL KRKQIWVLEP DPGQGTAVLF RSSHLGRYLS AEEDGRVACE MDQPGRDCRF LVLPQPDGRW VLQSEPHGRF FGGIEDRLSC FATAISPAEL WTVHLAIHPQ AHLLSVSRRR YVHLCLQEDE MAADGDMPWG VDALVTLIFQ SRRYCLKSYD SRYLRSDGRL VWEPEAHACY TLEFKAGKLA FKDCDGRYLA PVGPAGTLKA GRNTRPSKDE LFDLEQSHPQ VVLVAANRRY ISVRQGINVS ANQDEELGHE TFLMQIDQET KKCTFYSSTG GYWTLVTHGG IQATATQVSA NTMFEIEWHG RRVALKASNG RFVCMKKNGQ LAAISDFVGE DELFTLKLIN RPLLVLRGLD GFVCHRRGSN QLDTNRSTYD VFHLSFRDGA YQIRGRGGGF WYTGSHGSVC SDGDLAEDFL FEFRERGRLA IRALSGKYLR GGASGLLRAD ADLPVGEALW EY Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: Fascin 2 (FSCN2)

Alternative Name: Fscn2

Background: Fascin-2 (Retinal fascin),FUNCTION: Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis. Important for maintaining functional hair-cell bundles in the inner ear. May stiffen the longer stereocilia of hair-cell bundles in the inner ear enabling better force transmission to tip links. {ECO:0000269|PubMed:20660251}.

Molecular Weight: 55.1 kDa

UniProt: Q32M02

AlphaFold: Q32M02