HEXIM2 Protein (AA 1-313) (His tag)
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- Target See all HEXIM2 Proteins
- HEXIM2 (Hexamthylene Bis-Acetamide Inducible 2 (HEXIM2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-313
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HEXIM2 protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant Hexim2 Protein expressed in mammalian cells.
- Sequence
- MATVNHTNCN TASPAALEEA KTSGGLRSPQ IAHEPHDFGG SQLLPSGQEI QSEDEGTVPA GDGSSCNIRG SRTQSPGGCS VEAVLARKKH RRRPSKRKRH WRPYLELSWA EKQQRDERQS QRASRVREEM FAKGQPLAPY NTTQFLMNDR DLEEPNLDVL HGPSHSGSGG ENEAGDSDGQ GRAHGEFQQR DFSEAYERYH TESLQGRSKQ ELVRDYLDLE RRLSQAEQET RRLRQLQGCS SRQPCQQVEE LAAEVERLRT ENQRLRQENE MWNREGGYCD QEKPASEGTP WPKVEAPFQT HTGQLGHREA GDR Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product HEXIM2 Protein
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Hexamthylene Bis-Acetamide Inducible 2 (HEXIM2) (AA 1-286) protein (His tag)
custom-made HEXIM2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Hexamthylene Bis-Acetamide Inducible 2 (HEXIM2) protein (Myc-DYKDDDDK Tag)HEXIM2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- HEXIM2 (Hexamthylene Bis-Acetamide Inducible 2 (HEXIM2))
- Alternative Name
- Hexim2 (HEXIM2 Products)
- Background
- Protein HEXIM2,FUNCTION: Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. {ECO:0000250|UniProtKB:Q96MH2}.
- Molecular Weight
- 35.4 kDa
- UniProt
- Q3TVI4
- AlphaFold
- Q3TVI4
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