SKAP2 Protein (AA 1-358) (His tag)
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- Target See all SKAP2 Proteins
- SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-358
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SKAP2 protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant Skap2 Protein expressed in mammalian cells.
- Sequence
- MPNPSCTSSP GPLPEEIRNL LADVETFVAD TLKGENLSKK AKEKRESLIK KIKDVKSVYL QEFQDKGDAE DGDEYDDPFA GPADTISLAS ERYDKDDDGP SDGNQFPPIA AQDLPFVIKA GYLEKRRKDH SFLGFEWQKR WCALSKTVFY YYGSDKDKQQ KGEFAIDGYD VRMNNTLRKD GKKDCCFEIC APDKRIYQFT AASPKDAEEW VQQLKFILQD LGSDVIPEDD EERGELYDDV DHPAAVSSPQ RSQPIDDEIY EELPEEEEDT ASVKMDEQGK GSRDSVHHTS GDKSTDYANF YQGLWDCTGA LSDELSFKRG DVIYILSKEY NRYGWWVGEM KGAIGLVPKA YLMEMYDI Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Src Kinase Associated Phosphoprotein 2 (SKAP2) (AA 1-359) protein (His tag)
custom-made SKAP2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Src Kinase Associated Phosphoprotein 2 (SKAP2) (AA 1-359) protein (GST tag)SKAP2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Src Kinase Associated Phosphoprotein 2 (SKAP2) protein (Myc-DYKDDDDK Tag)SKAP2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))
- Alternative Name
- Skap2 (SKAP2 Products)
- Background
- Src kinase-associated phosphoprotein 2 (Pyk2/RAFTK-associated protein) (SKAP55 homolog) (SKAP-HOM) (Src family-associated phosphoprotein 2) (Src kinase-associated phosphoprotein 55-related protein) (Src-associated adapter protein with PH and SH3 domains),FUNCTION: May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway. {ECO:0000269|PubMed:11063873, ECO:0000269|PubMed:15894167, ECO:0000269|PubMed:16135797}.
- Molecular Weight
- 40.7 kDa
- UniProt
- Q3UND0
- AlphaFold
- Q3UND0
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