CENPW Protein (AA 1-86) (Fc Tag)
custom-made
CENPW
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all CENPW Proteins
- CENPW (Centromere Protein W (CENPW))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-86
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CENPW protein is labelled with Fc Tag.
- Purpose
- Predefined custom protein recombinant Cenpw Protein expressed in mammalian cells.
- Sequence
- MAPSTTVTRR VKRKAPRAFL KRTLKQKKPH LGLGRCCDLL IHLNCLLFIQ RLAEESRTNA CESKSRVIKK DHVLAAGKVI LKKSRG Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product CENPW Protein
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Centromere Protein W (CENPW) (AA 1-88) protein (His tag)
custom-made CENPW Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Centromere Protein W (CENPW) (AA 1-88) protein (GST tag)CENPW Origin: Human Host: Wheat germ Recombinant ELISA, AA, AP, WB
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- CENPW (Centromere Protein W (CENPW))
- Alternative Name
- Cenpw (CENPW Products)
- Background
- Centromere protein W (CENP-W) (Cancer-up-regulated gene 2 protein),FUNCTION: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity). Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPW has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis (By similarity). {ECO:0000250, ECO:0000269|PubMed:17610844}.
- Molecular Weight
- 9.7 kDa
- UniProt
- Q3URR0
- AlphaFold
- Q3URR0
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