FUZ Protein (AA 1-415) (His tag)
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- Target See all FUZ Proteins
- FUZ (Fuzzy Homolog (FUZ))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-415
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FUZ protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant Fuz Protein expressed in mammalian cells.
- Sequence
- MGDEGPGSPV HLLCLAASSG VPLFCRSSSG GAPSRQQLPF SVIGSLNGVH MFGQNLDVQL NSARTEDTTV VWKNFHDSIT LIVLSSEEGT SELRLERMLH MVFGAMVLIV GLEELTNIRN VERLKKELRA SYCLIDSFLG NSELIGDLTQ CVDCVIPPEG SAMQETLSGF AEATGTAFVS LLVSGRVVAA TEGWWRLGMP EAVLLPWLVG SLPPQAARDY PVYLPHGSPT VPHRLLTLTL LRGLELCLLC GPRPPLGQLD PQLMERWWQP LLEPLRACLP LGPRALPEGF PLHSDILGLL LLHLELRRCL FTMEPSKDKE PSPEQRRRLL RNFYTLVATT HFPPEPGPAE KQEDTVYPAQ MPRACYLVLG PGMGWQLVAV QLGLRLLLLL LSPHTPTHGL RSLATRTLQA LTPLL Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Fuzzy Homolog (FUZ) (AA 1-418) protein (His tag)
custom-made FUZ Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Fuzzy Homolog (FUZ) protein (Myc-DYKDDDDK Tag)FUZ Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- FUZ (Fuzzy Homolog (FUZ))
- Alternative Name
- Fuz (FUZ Products)
- Background
- Protein fuzzy homolog,FUNCTION: Probable planar cell polarity effector involved in cilium biogenesis. May regulate protein and membrane transport to the cilium. Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:19877275, PubMed:19767740, PubMed:27158779). May regulate the morphogenesis of hair follicles which depends on functional primary cilia (PubMed:20962855). {ECO:0000269|PubMed:19767740, ECO:0000269|PubMed:19877275, ECO:0000269|PubMed:20962855, ECO:0000305|PubMed:27158779}.
- Molecular Weight
- 45.6 kDa
- UniProt
- Q3UYI6
- AlphaFold
- Q3UYI6
- Pathways
- Tube Formation, Embryonic Body Morphogenesis
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