RAP1GAP2 Protein (AA 1-712) (His tag)

Catalog No. ABIN7557543

Recombinant RAP1GAP2 protein expressed in HEK-293 Cells.

Quick Overview for RAP1GAP2 Protein (AA 1-712) (His tag) (ABIN7557543)

Target: RAP1GAP2 (RAP1 GTPase Activating Protein 2 (RAP1GAP2))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-712

Purification tag / Conjugate: This RAP1GAP2 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Rap1gap2 Protein expressed in mammalian cells.

Sequence: MLAGLKVKKQ ELANSSDVTL PDRPLSPPLT APPTMKSAEF FEMLEKMQGI KLEEQRPGPQ KNKDDYIPYP SIDEVVEKGG PYPLIILPQF GGYWIEDPEN VGTPTSLGSS VYEEEEEDSL SPNTFGYKLE CRGEARAYRR HFLGKDHLNF YCTGSSLGNL ILSIKCEEAE GMEYLRIILR SKLKTVHERI PLAGLSKLPS VPQIAKAFCD DAVGLKFNPV LYPKASQMIV SYDEHDVNNT FKFGVIYQKA RQTLEEELFG NNEESPAFKE FLDLLGDTIT LQDFKGFRGG LDVTHGQTGV ESVYTTFRDR EIMFHVSTKL PFTDGDTQQL QRKRHIGNDI VAIIFQEENT PFVPDMIASN FLHAYIVVQA DNPGTETPSY KVSVTAREDV PAFGPPLPSP PVFQKGAEFR EFLLTKLTNA ENACCKSDKF AKLEDRTRAA LLDNLHDELH THTQVMLGMG PEEDKFENGG HGGFLESFKR AIRVRSHSME TMVGSQRKLH GGNLPGSLSG GIVHNSMEVT KTTFSPPVAA ATAKNQSRSP IKRRSGLFPR LHSGSEGQGD SRTRCDSASS TPKTPDGGHS SQEIKSETSS NPSSPEICPN KEKPFIKLKE NGRANISRSS SSTSSFSSTA GEGEAMEECD SGSSQPSTTS PFKQEVFAYS PSPSSESPSL GAAATPIIMS RSPTDAKSRN SPRSNLKFRF DKLSHASSSA GH Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: RAP1GAP2 (RAP1 GTPase Activating Protein 2 (RAP1GAP2))

Alternative Name: Rap1gap2

Background: Rap1 GTPase-activating protein 2 (Rap1GAP2) (GTPase-activating Rap/Ran-GAP domain-like protein 4),FUNCTION: GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state. {ECO:0000250}.

Molecular Weight: 78.3 kDa

UniProt: Q5SVL6

AlphaFold: Q5SVL6