SLC5A10 Protein (AA 1-596) (His tag)

Catalog No. ABIN7557550

Product Details

Target: SLC5A10 (Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 10 (SLC5A10))

Protein Type: Recombinant

Protein Characteristics: AA 1-596

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This SLC5A10 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Slc5a10 Protein expressed in mammalian cells.

Sequence: MAGNSTGDAH VPGSQLSVTD IIVISVYFAL NVAVGIWSAC RANKNTVSGY FLAGRDMAWW PIGASLFASS EGSGLFVGLA GSGAAGGLAV AGFEWNATYV LLALAWVFVP IYISSEIVTL PEYIQKRFGG QRIRTYLSVL SLMLSVFTKI SIDLYAGALF VHICLGWNFY LSTILTLAIT ALYTIAGGLA TVIYTDALQT IIMVVGAVIL AVKAFNQIGG YEQLEAAYAQ AIPSRTIPNT TCHLPRADAM HMFRDPSTGD LPWTGMTFGL TIMATWYWCT DQVIVQRSLS ARNLNHAKAG SILASYLKML PMGLMIMPGM ISRVLFPDDV GCVVPSECLR ACGAEIGCSN IAYPKLVMEL MPIGLRGLMI AVMMAALLSS LTSIFNSSST LFTMDIWRQL RPSAGERELL LVGRLVIVVL IGVSVAWIPV LQGSNSGQLF IYMQSVTSSL APPVTAIFIL GIFWRRANEQ GAFWGLMAGL VVGALRLVLE FLYPEPPCGQ IDTRPAPLRS LHYLHFAIAL FLLTCAVMAA GSLLSPPPQQ RQIENLTWWT LAPNWSLGTK TGDGQTPQKR AFWARVCNVN AIFLMCVNIF FYAYFA Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: SLC5A10 (Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 10 (SLC5A10))

Alternative Name: Slc5a10 (SLC5A10 Products)

Background: Sodium/mannose cotransporter SLC5A10 (Sodium/glucose cotransporter 5) (Na(+)/glucose cotransporter 5) (Solute carrier family 5 member 10),FUNCTION: Electrogenic Na+-coupled sugar symporter that actively transports D-mannose or D-fructose at the plasma membrane, with a Na+ to sugar coupling ratio of 1:1. Transporter activity is driven by a transmembrane Na+ electrochemical gradient set by the Na+/K+ pump. Exclusively recognizes sugar substrates having a pyranose ring with an axial hydroxyl group on carbon 2 (PubMed:23451068) (By similarity). Has likely evolved to enable renal reabsorption of D-mannose, an important constituent of oligosaccharide chains of glycoproteins. Contributes to dietary D-fructose reabsorption from glomerular filtrate across the brush border of the kidney (PubMed:23451068) (By similarity). {ECO:0000250|UniProtKB:A0PJK1, ECO:0000269|PubMed:23451068}.

Molecular Weight: 64.7 kDa

UniProt: Q5SWY8

AlphaFold: Q5SWY8