JKAMP Protein (AA 1-311) (His tag)

Catalog No. ABIN7558669

This Recombinant JKAMP protein is produced in HEK-293 Cells.

Quick Overview for JKAMP Protein (AA 1-311) (His tag) (ABIN7558669)

Target: JKAMP (JNK1/MAPK8-Associated Membrane Protein (JKAMP))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-311

Purification tag / Conjugate: This JKAMP protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Jkamp Protein expressed in mammalian cells.

Sequence: MAVDIQPACL GLYCGKTLLF KNGSSEIYGE CGVCPRGQRT NAQKYCQPCT ESPELYDWLY LGFMAMLPLV LHWFFIEWYS GKKSSSALFQ HITALFECTM AAIITLLVSD PVGVLYIRSC RVLMLSDWYT MLYNPSPDYV TTVHCTHEAV YPLYTIVFVY YAFCLVLMML LRPLLVKKIA CGLGKSDRFK SIYAALYFFP ILTVLQAVGG GLLYYAFPYI ILVLSLVTLA VYMSASEIEN CYDLLVRKKR LIVLFSHWLL HAYGIVSISR VDRLEHDLPL LALVPTPALF YLFTAKFTEP SRILSEGANG H Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: JKAMP (JNK1/MAPK8-Associated Membrane Protein (JKAMP))

Alternative Name: Jkamp

Background: JNK1/MAPK8-associated membrane protein (JKAMP) (JNK1-associated membrane protein) (JAMP) (Medulloblastoma antigen MU-MB-50.4 homolog),FUNCTION: Regulates the duration of MAPK8 activity in response to various stress stimuli (PubMed:16166642). Facilitates degradation of misfolded endoplasmic reticulum (ER) proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system (PubMed:18784250). {ECO:0000269|PubMed:16166642, ECO:0000269|PubMed:18784250}.

Molecular Weight: 35.2 kDa

UniProt: Q8BI36

AlphaFold: Q8BI36