DYRK4 Protein (AA 1-632) (His tag)

Catalog No. ABIN7558670

Product Details

Target: DYRK4 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 4 (DYRK4))

Protein Type: Recombinant

Protein Characteristics: AA 1-632

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This DYRK4 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Dyrk4 Protein expressed in mammalian cells.

Sequence: MQLLRLPALT RTETSMDTNK ARKRSLTTFP ILKARKKQSF TSVKVESKPL GHLQKPSSKN KKLRVNRCPQ KIPSNTAFPF VDTKGKRNTV NFPQIGNKVP SKGPMQYQEN QIHNQVLSSE LKTSEIPFNI NTKAQDTKPH PELQKKHKVP LTVAEALKFF KNQLSPYEQS EILGYSELWF LGLEAKKLNV VPEKFSKTSF DDEHGSYMKV LHDHIAYRYE VLEMIGKGSF GQVAKCLDHK NNELVALKII RNKKRFHHQA LVELKILEAL RRKDKDNNHN VVHMKDFFYF RNHLCITFEL LGINLYELMK NNSFHGFNLS IVRRFTFSIL KCLHMLYVEK IIHCDLKPEN IVLYQRGQVT VKVIDFGSSC YEHQKVYTYI QSRFYRSPEV ILGHPYNMAI DMWSLGCIMA ELYTGYPLFP GENEVEQLAC IMEVLGLPPA HFTQTASRRQ VFFDSKGLPK NINNNRGGKR YPDSKDLTMV VKTYDSSFLD FLRRCLVWEP SLRMTPEQAL KHAWIHEPRK FKPRPKPQIL RKPGASISSE ISTEKAEEQQ ASKGKKDEAT KETTDKLKDE AEKHLENSGK QQSSVEHTAD TIQLPHLTEA SGKSETVAGS EMSAEQQSTS SPKSTNILPP IV Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: DYRK4 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 4 (DYRK4))

Alternative Name: Dyrk4 (DYRK4 Products)

Background: Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1),FUNCTION: Possible non-essential role in spermiogenesis. {ECO:0000269|PubMed:17292540}.

Molecular Weight: 72.6 kDa

UniProt: Q8BI55

AlphaFold: Q8BI55