NARS Protein (AA 1-559) (His tag)

Catalog No. ABIN7558795

Product Details

Target: NARS (Asparaginyl-tRNA Synthetase (NARS))

Protein Type: Recombinant

Protein Characteristics: AA 1-559

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This NARS protein is labelled with His tag.

Purpose: Made-to-order recombinant Nars1 Protein expressed in mammalian cells.

Sequence: MSSEVIRGTA EMVLAELYVS DREGNDATGD GTKEKPFKTG LKALMTVGKE PFPTIYVDSQ KENERWDVIS KSQMKNIKKM WHREQMKNDS REKKEAEDNL RREKNLEEAK KIIIKNDPSL PEPACVKISA LEGYRGQRVK VFGWVHRLRR QGKNLMFLVL RDGTGYLQCV LSDDLCQCYN GVVLSTESSV AVYGTLNLTP KGKQAPGGHE LSCDFWELVG LAPAGGADNL INEESDVDVQ LNNRHMMIRG ENMSKILKAR SMITRCFRDH FFDRGYCEVT TPTLVQTQVE GGATLFKLDY FGEEAFLTQS SQLYLETCLP ALGDVFCIAQ SYRAEQSRTR RHLAEFTHVE AECPFLTFED LLNRLEDLVC DVVDRVLKSP VASIVYELNP NFKPPKRPFR RMNYSDAIEW LKEHDVKKED GTFYEFGDDI PEAPERLMTD TINEPILLCR FPVEIKSFYM QRCPEDPRLT ESVDVLMPNV GEIVGGSMRS WDSEEILEGY KREGIDPAPY YWYTDQRKYG TCPHGGYGLG LERFLSWILN RYHIRDVCLY PRFLQRCRP Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: NARS (Asparaginyl-tRNA Synthetase (NARS))

Alternative Name: Nars1 (NARS Products)

Background: Asparagine--tRNA ligase, cytoplasmic (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS) (Asparaginyl-tRNA synthetase 1),FUNCTION: Catalyzes the attachment of asparagine to tRNA(Asn) in a two-step reaction: asparagine is first activated by ATP to form Asn-AMP and then transferred to the acceptor end of tRNA(Asn). In addition to its essential role in protein synthesis, acts as a signaling molecule that induced migration of CCR3-expressing cells. Has an essential role in the development of the cerebral cortex, being required for proper proliferation of radial glial cells. {ECO:0000250|UniProtKB:O43776}.

Molecular Weight: 64.3 kDa

UniProt: Q8BP47

AlphaFold: Q8BP47