SLC15A3 Protein (AA 1-578) (His tag)

Catalog No. ABIN7558808

This Recombinant SLC15A3 protein is expressed in HEK-293 Cells.

Quick Overview for SLC15A3 Protein (AA 1-578) (His tag) (ABIN7558808)

Target: SLC15A3 (Solute Carrier Family 15 Member 3 (SLC15A3))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-578

Purification tag / Conjugate: This SLC15A3 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Slc15a3 Protein expressed in mammalian cells.

Sequence: MSAPRAEEQP SRSGERQPLV ARGPRGPRRW RRTAAAAVLL VQMLERAAFF GVTSNLVLYL NSLNFNWDGQ QASRATLLFL GASYLLAPVG GWLADVYLGR FLTISLSLLL YLAASGLLLT TITNDGRRSF CGEMPELPLE PACPSSSCQG SWSSPYCATT LYLVLLLLAL AASSVRSTLT SFGADQVMDL GRDATRRFFN WFYWSINLGA ILSLLVVAFI EQNISFLWGY SIIVGLVGLA FFIFLFATPV FITKPPTGSQ VSSMLKLAFQ NCCPCRRSSS RDSESAHLLP DQRSNQPGPS PQEDMANFQV LVKILPVMVT LVPYWMVYFQ MQSTYVLQGL HLHIPNIFRT NPNISLLLRS DSSNYRIPEA WLLLANVAVI LILIPVKDHL IDPLLLRCKL LPSSLQKMAL GMFFGFTSII VAGVLEKERL QYIAANQTVP QLIGKDLYYA APLSIWWQIP QYLLIGVSEI FASIPGLEFA YSEAPRSMQG AIMGIFFCLS GVGSLLGSGL VALLSFPGGW MYCPKDFGNI NNCQMDRYFF LLAGIEAVTA VLFLWIAGRY ERTRQDPASQ RSSSRVRG Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: SLC15A3 (Solute Carrier Family 15 Member 3 (SLC15A3))

Alternative Name: Slc15a3

Background: Solute carrier family 15 member 3 (Peptide transporter 3) (Peptide/histidine transporter 2) (cAMP-inducible gene 1 protein),FUNCTION: Proton-coupled amino-acid transporter that transports free histidine and certain di- and tripeptides, and is involved in innate immune response (PubMed:24695226). Also able to transport carnosine (By similarity). Involved in the detection of microbial pathogens by toll-like receptors (TLRs) and NOD-like receptors (NLRs), probably by mediating transport of bacterial peptidoglycans across the endolysosomal membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand (PubMed:24695226). {ECO:0000250|UniProtKB:Q8IY34, ECO:0000269|PubMed:24695226}.

Molecular Weight: 64.1 kDa

UniProt: Q8BPX9

AlphaFold: Q8BPX9