RCCD1 Protein (AA 1-377) (His tag)
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- Target See all RCCD1 products
- RCCD1 (RCC1 Domain Containing 1 (RCCD1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-377
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RCCD1 protein is labelled with His tag.
- Purpose
- Made-to-order recombinant Rccd1 Protein expressed in mammalian cells.
- Sequence
- MAEKRHGAWF GFGFCGFGQA LGSGNSHHSV YSPEPLHASD DICQVSAGWS YTALVTRGGR VELSGSVSGA ADGCRDVWAS EELLVLLRNK GGSSTEVQAW VPGSALQGEP LWVQNLVSGA KGQGEDEPSR ESRMGTLPLL PCARAYVTPE PPFCQPLAPE LRVRQLELGA EHVLLLCAAG QVFSWGAGRH GQLGHGTLEA ELEPRLLEAL QGLRMAKVAA GGWHSVCLSE TGDIYIWGWN ESGQLALPTR SGTENKAERE EATELNEDGL KEELAVADAG APAHFIAIQP FPALLDLPLG SDAVMASCGS RHTAVVTRTG ELYTWGWGKY GQLGHKDSTS LDRPCCVEYF VERQLEVRAV TCGPWNTYVY AMERDKS Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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RCC1 Domain Containing 1 (RCCD1) (AA 1-376) protein (His tag)
custom-made RCCD1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
RCC1 Domain Containing 1 (RCCD1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)RCCD1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- RCCD1 (RCC1 Domain Containing 1 (RCCD1))
- Alternative Name
- Rccd1 (RCCD1 Products)
- Background
- RCC1 domain-containing protein 1,FUNCTION: Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8. {ECO:0000250|UniProtKB:A6NED2}.
- Molecular Weight
- 40.6 kDa
- UniProt
- Q8BTU7
- AlphaFold
- Q8BTU7
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