TMEM120A Protein (AA 1-343) (His tag)
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- Target See all TMEM120A products
- TMEM120A (Transmembrane Protein 120A (TMEM120A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-343
- Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TMEM120A protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant Tmem120a Protein expressed in mammalian cells.
- Sequence
- MQSPPPDPLG DCLRNWEDLQ QDFQGIQETH RLYRLKLEEL TKLQANCTNS ITRQKKRLQE LALVLKKCRP SLPSESMEAA QELENQMKER QGLFFDMEAY LPKKNGLYLS LVLGNVNVTL LSKQAKFAYK DEYEKFKLYL TIILIVISFT CRFLLNSRVT DAAFNFLLVW YYCTLTIRES ILINNGSRIK GWWVFHHYVS TFLSGVMLTW PDGLMYQKFR NQFLSFSMYQ SFVQFLQYYY QSGCLYRLRA LGERHTMDLT VEGFQSWMWR GLTFLLPFLF FGHFWQLFNA LTLFNLARDP ECKEWQVLMC GFPFLLLFLG NFFTTLRVVH QKFHSQQHGN KKD Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Transmembrane Protein 120A (TMEM120A) (AA 1-343) protein (His tag)
custom-made TMEM120A Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Transmembrane Protein 120A (TMEM120A) (AA 1-343) protein (GST tag)TMEM120A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Transmembrane Protein 120A (TMEM120A) protein (Myc-DYKDDDDK Tag)TMEM120A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- TMEM120A (Transmembrane Protein 120A (TMEM120A))
- Alternative Name
- Tmem120a (TMEM120A Products)
- Background
- Ion channel TACAN (Transmembrane protein 120A),FUNCTION: Ion channel involved in sensing mechanical pain (PubMed:32084332). Contributes to mechanosensitive currents in nocireceptors and detecting mechanical pain stimuli (PubMed:32084332). May also be required for efficient adipogenesis (PubMed:26024229). {ECO:0000269|PubMed:26024229, ECO:0000269|PubMed:32084332}.
- Molecular Weight
- 40.8 kDa
- UniProt
- Q8C1E7
- AlphaFold
- Q8C1E7
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