WDPCP Protein (AA 1-722) (His tag)

Catalog No. ABIN7559130

Product Details

Target: WDPCP (WD Repeat Containing Planar Cell Polarity Effector (WDPCP))

Protein Type: Recombinant

Protein Characteristics: AA 1-722

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This WDPCP protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Wdpcp Protein expressed in mammalian cells.

Sequence: MSFCLTELHL WSLKSTLHIA DRDIGVYQYY DKKDPSVSAT EHGNLEEKQR LAESRDYPWT LKNRRPEKLR DSLKELEELM QSSPCVLSKW KSKYICQLLF GSGVLVSLSL SGPQLEKVVI DRSLVGKLIS DTISDALLTD SFIILSFLAQ NKLCFIQFTK KMDSLDGNKR LEKLSALDLK ISYYDIPGPA NRTIDRHLAV NSTQDLVVCW WPLVSDDVWP WTPVSSEKDR ANMLLLGFTQ GGLEVLSFVR TEWSPLDVHF GTKQPYQVFT VECSVSVDKE PMADSCIYES VRNKLHCVSV TRIPLRSKAI SCCRNSTEDK LIVGCEDSSV ILYEAHRGVT LLAQAELRPS LISCHPSGAI LLVGSNQGEL QIFDIALSPI NIQLLAEDYS PKETLQFKKF FDVSSSLVQM QWMAPPVVFQ KPKRGEICDL LFLRFNKGPL GVLLFKLGIL TRGQLGLVDL ILQYIHYSEV YEAISILRSM DWDTLGQQCL IGMGTIVNHL LRQRLTPERE AQLEASLGTF YAPTRPLLDT TILEYREPVS KYARRLFHHL LRYKRFEKAF LLAVDIGARD LFMDIHYLAL DMGELALAEV ARRRAHDIDV ESVSSGVELL GPLDRRDMLN EGFASSALMP EGENKFPGLL PSIGSTHMQT LQQKIPNGPS SRWAIERRTE EEEEEEEEEE EELCTDSSGA TTWNAEGELK EDQRKQDIGD VGSLRMVHFG LV Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: WDPCP (WD Repeat Containing Planar Cell Polarity Effector (WDPCP))

Alternative Name: Wdpcp (WDPCP Products)

Background: WD repeat-containing and planar cell polarity effector protein fritz homolog (mFrtz) (Homolog-13) (WD repeat-containing and planar cell polarity effector protein),FUNCTION: Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779). {ECO:0000250|UniProtKB:Q32NR9, ECO:0000305|PubMed:27158779}.

Molecular Weight: 81.7 kDa

UniProt: Q8C456

AlphaFold: Q8C456