STAC2 Protein (AA 1-408) (His tag)
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- Target See all STAC2 products
- STAC2 (SH3 and Cysteine Rich Domain 2 (STAC2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-408
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This STAC2 protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant Stac2 Protein expressed in mammalian cells.
- Sequence
- MTEMSEKENE PDDAATHTPP GTVSTLQETK LQRFKRSLSL KTILRSKSVE NFFLRSGSEL KCPTEVLLTP PTPLPPPSPP PASTDRGLPT PTPSPCPVPR PLAPLKPVRL HSFQEHVFKR ASPCELCHQL IVGNSKQGLR CKTCKVSVHL WCSEEISHQQ CPGKTSTSFR RNFSSPLLVH APPPACAMNK ESPPTGTSGK VDPVYETLRY GTSLALMNRS SFSSTSESPT RSLSERDELT EDGEGSIRSS EEGPGDSVFT APAESEGSGP EEKSPGQQPP KLPLRKDVGP MYSYVALYKF LPQENNDLAL QPGDRIMLVD DSNEDWWKGK IGDRVGFFPA NFVQRVRPGE NVWRCCQPFS GNKEQGYMSL KENQICVGVS RSKDSDGFIR VSSGKKRGLV PADSLAEI Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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SH3 and Cysteine Rich Domain 2 (STAC2) (AA 1-411) protein (His tag)
custom-made STAC2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
SH3 and Cysteine Rich Domain 2 (STAC2) protein (Myc-DYKDDDDK Tag)STAC2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- STAC2 (SH3 and Cysteine Rich Domain 2 (STAC2))
- Alternative Name
- Stac2 (STAC2 Products)
- Background
- SH3 and cysteine-rich domain-containing protein 2 (24b2/STAC2) (Src homology 3 and cysteine-rich domain-containing protein 2),FUNCTION: Plays a redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel activity (PubMed:29467163). Slows down the inactivation rate of the calcium channel CACNA1C (PubMed:25548159, PubMed:29363593). {ECO:0000269|PubMed:25548159, ECO:0000269|PubMed:29363593, ECO:0000269|PubMed:29467163}.
- Molecular Weight
- 44.8 kDa
- UniProt
- Q8R1B0
- AlphaFold
- Q8R1B0
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