ETV3 Protein (AA 1-513) (His tag)
-
- Target See all ETV3 Proteins
- ETV3 (Ets Variant 3 (ETV3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-513
-
Origin
- Mouse
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ETV3 protein is labelled with His tag.
- Purpose
- Made-to-order recombinant Etv3 Protein expressed in mammalian cells.
- Sequence
- MKAGCSIVEK PEGGGGYQFP DWAYKAESSP GSRQIQLWHF ILELLQKEEF RHVIAWQQGE YGEFVIKDPD EVARLWGRRK CKPQMNYDKL SRALRYYYNK RILHKTKGKR FTYKFNFNKL VMPNYPFINI RSSGVVPQSA PPVPTASSRF HFPPLDSHSP TGDVQPGRFS ASSLSASGPE SGVTTDRKVE PSDLEDGSAS DWHRGMDFMP SRNALGGGAV GHQKRKPDIL LPLFTRPAMY PDPHSPFAIS PVPGRGGVLN VPISPALSLT PTMFSYSPSP GLSPFTSSSC FSFNPEEMKH YLHSQACSVF NYHLSPRTFP RYPGLMVPPL QCQMHPEEPS QFSIKLQPPP AGRKNRERVE SREEAVRGSV PASAPVPSRI KVEPATEKDP DSLRQSTQGK EEQTQEVDSM RSRTIEEGKG TGFAHPSPTW PSVSISTPSD EPLEGTEDSE DRSVREPGVP EKKEDALMPP KLRLKRRWND DPEARELNKT GKFLWNGAGP QGLATTATAA ADA Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
-
Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
-
Ets Variant 3 (ETV3) (AA 1-512) protein (His tag)
custom-made ETV3 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Ets Variant 3 (ETV3) (AA 1-143) protein (GST tag)ETV3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Ets Variant 3 (ETV3) protein (His tag)ETV3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
-
- Target
- ETV3 (Ets Variant 3 (ETV3))
- Alternative Name
- Etv3 (ETV3 Products)
- Background
- ETS translocation variant 3 (ETS domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor),FUNCTION: Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity. {ECO:0000269|PubMed:10913304, ECO:0000269|PubMed:12007404}.
- Molecular Weight
- 57.0 kDa
- UniProt
- Q8R4Z4
- AlphaFold
- Q8R4Z4
-
